PIP4K2B: phosphatidylinositol-5-phosphate 4-kinase type 2 beta
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1bo1 chain A
1bo1 chain B
3wzz chain A
3wzz chain B
3x01 chain A
3x01 chain B
3x02 chain A
3x02 chain B
3x03 chain A
3x03 chain B
3x04 chain A
3x04 chain B
3x05 chain A
3x05 chain B
3x06 chain A
3x06 chain B
3x07 chain A
3x07 chain B
3x08 chain A
3x08 chain B
3x09 chain A
3x09 chain B
3x0a chain A
3x0a chain B
3x0b chain A
3x0b chain B
3x0c chain A
3x0c chain B
6k4g chain A
6k4g chain B
6k4h chain A
6k4h chain B
7em1 chain A
7em1 chain B
7em2 chain A
7em2 chain B
7em3 chain A
7em3 chain B
7em4 chain A
7em4 chain B
7em5 chain A
7em5 chain B
7em6 chain A
7em6 chain B
7em7 chain A
7em7 chain B
7em8 chain A
7em8 chain B
7n80 chain A
7n80 chain B
7n81 chain A
7n81 chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S131 SAPINSDS QGRCGTR 1 44 - - - - - - 44 - - - - - - - - - - - - - S319 VGGNLLCS YGTPPDS 3 22 - - 4 4 - - - - - - - - 4 4 - - 4 2 - - T322 NLLCSYGT PPDSPGN 10 510 9 - 4 4 83 78 78 - 19 8 5 5 4 4 34 9 58 25 65 18 S326 SYGTPPDS PGNLLSF 6 238 - - - - 42 47 41 - 18 11 4 4 - - - - 42 20 7 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S131 SAPINSDS QGRCGTR - - - - - - - - - - - S319 VGGNLLCS YGTPPDS - - - - - - - - - - - T322 NLLCSYGT PPDSPGN -3.2e-3 - - -6.6e-3 - - - - - -0.018 -0.98 S326 SYGTPPDS PGNLLSF -0.1 - - 0.95 - - - - - -0.018 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S131
S319
T322
S326
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S131 S319 T322 S326 protein RNA SCNV methylation CCRCC S131 S319 T322 S326 protein RNA SCNV methylation COAD S131 S319 T322 S326 protein RNA SCNV methylation GBM S131 S319 T322 S326 protein RNA SCNV methylation HNSCC S131 S319 T322 S326 protein RNA SCNV methylation LSCC S131 S319 T322 S326 protein RNA SCNV methylation LUAD S131 S319 T322 S326 protein RNA SCNV methylation OV S131 S319 T322 S326 protein RNA SCNV methylation PDAC S131 S319 T322 S326 protein RNA SCNV methylation UCEC S131 S319 T322 S326 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S131
S319
T322
S326
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S131
S319
T322
S326
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.