Protein: ENSP00000483983

BIN2:: bridging integrator 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
T124	LADQAVRTMEIYVAQ	1	9	-	-	-	-	3	6	-	-	-	-	-	-	-	-	-	-	-	-	-	-
S255	VVKGLSSSSRRSLVI	4	73	-	-	-	-	-	-	8	-	12	8	10	10	-	-	19	6	-	-	-	-
S256	VKGLSSSSRRSLVIS	9	762	75	-	12	4	-	-	36	-	56	32	88	80	83	78	48	10	78	32	39	11
S259	LSSSSRRSLVISPPV	9	1300	104	-	103	80	-	-	99	-	108	62	108	99	98	88	83	19	97	39	95	18
S263	SRRSLVISPPVRTAT	9	491	16	-	8	-	-	-	35	-	43	22	98	91	26	23	62	15	10	5	35	2
S273	VRTATVSSPLTSPTS	9	1173	89	-	91	68	-	-	81	-	103	59	108	99	101	92	39	10	89	38	90	16
T276	ATVSSPLTSPTSPST	6	71	8	-	5	4	-	-	-	-	11	7	5	4	5	4	-	-	12	6	-	-
S277	TVSSPLTSPTSPSTL	8	611	62	-	27	11	-	-	72	-	33	21	78	73	87	81	-	-	31	11	24	-
T279	SSPLTSPTSPSTLSL	8	237	27	-	29	20	-	-	26	-	5	3	10	9	31	28	-	-	16	5	19	9
S280	SPLTSPTSPSTLSLK	9	314	17	-	13	11	-	-	44	-	48	27	5	5	14	12	12	5	45	23	28	5

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
T124	LADQAVRTMEIYVAQ	-	-	-	-	-	-	-	-	-	-	-
S255	VVKGLSSSSRRSLVI	-	-	-	-	-	-	-	-	-	-	-
S256	VKGLSSSSRRSLVIS	-0.99	-	-	-	-	-0.78	-0.11	-0.68	0.51	0.17	0.85
S259	LSSSSRRSLVISPPV	-2.4e-5	-	9.1e-22	-	-	0.03	-1.3e-17	-1e-23	-2.2e-4	4.2e-6	-1.0e-4
S263	SRRSLVISPPVRTAT	-1.5e-6	-	-	-	-	0.02	-1.8e-8	-1.0e-4	-0.015	-	-
S273	VRTATVSSPLTSPTS	-0.94	-	1e-12	-	-	0.036	-7.9e-14	-1.3e-11	-0.028	8e-8	0.041
T276	ATVSSPLTSPTSPST	-	-	-	-	-	-	-	-	-	-	-
S277	TVSSPLTSPTSPSTL	-2.6e-5	-	0.21	-	-	-0.02	-7.5e-8	-2.6e-5	-	0.21	-
T279	SSPLTSPTSPSTLSL	0.26	-	5.4e-5	-	-	-	-	-0.014	-	-	-
S280	SPLTSPTSPSTLSLK	0.098	-	-	-	-	-0.87	-	-	-	0.013	-

Showing 1 to 10 of 55 rows

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000483983Gene: BIN2

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000483983
Gene: BIN2