LRMP: inositol 1,4,5-triphosphate receptor associated 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y510 SLQKKGLY IEELKST 2 26 - - - - - - 9 - - - - - - - - - - - 17 - S961 IRMNDDPS MEENGVE 1 9 - - - - - - - - - - - - 4 5 - - - - - - S978 CPESLLQS REYSSLP 4 67 - - 5 4 - - - - - - 5 5 19 16 - - 9 4 - - S983 LQSREYSS LPLPRHT 5 123 - - 17 8 - - - - 12 5 20 18 - - - - 27 9 5 2 S991 LPLPRHTS STDGTIT 1 9 - - - - - - 9 - - - - - - - - - - - - - S1030 EEDTRSAS PTIEAQG 7 429 - - 8 8 - - 73 - 38 25 19 18 55 48 - - 55 22 53 7 T1032 DTRSASPT IEAQGTS 2 23 - - 4 4 - - - - - - - - 8 7 - - - - - - T1038 PTIEAQGT SPAHDNI 3 39 - - 17 8 - - 9 - - - - - - - - - 4 1 - - S1039 TIEAQGTS PAHDNIA 3 23 - - 4 4 - - - - 7 3 - - - - - - 4 1 - - S1078 EHKKEHAS GDSVVSP 2 25 - - 8 8 - - - - 5 4 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y510 SLQKKGLY IEELKST - - - - - - - - - - - S961 IRMNDDPS MEENGVE - - - - - - - - - - - S978 CPESLLQS REYSSLP - - - - - - - - - - - S983 LQSREYSS LPLPRHT -0.76 - - - - - -0.76 - - - - S991 LPLPRHTS STDGTIT - - - - - - - - - - - S1030 EEDTRSAS PTIEAQG -3.2e-6 - - - - -0.52 - -0.03 - -1.5e-7 - T1032 DTRSASPT IEAQGTS - - - - - - - - - - - T1038 PTIEAQGT SPAHDNI - - - - - - - - - - - S1039 TIEAQGTS PAHDNIA - - - - - - - - - - - S1078 EHKKEHAS GDSVVSP - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y510
S961
S978
S983
S991
S1030
T1032
T1038
S1039
S1078
S1084
S1244
S1262
S1268
S1269
T1274
S1277
S1298
S1309
S1312
S1317
T1324
Y1325
S1326
S1343
S1346
T1350
S1358
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y510 S961 S978 S983 S991 S1030 T1032 T1038 S1039 S1078 S1084 S1244 S1262 S1268 S1269 T1274 S1277 S1298 S1309 S1312 S1317 T1324 Y1325 S1326 S1343 S1346 T1350 S1358 protein RNA SCNV methylation CCRCC Y510 S961 S978 S983 S991 S1030 T1032 T1038 S1039 S1078 S1084 S1244 S1262 S1268 S1269 T1274 S1277 S1298 S1309 S1312 S1317 T1324 Y1325 S1326 S1343 S1346 T1350 S1358 protein RNA SCNV methylation COAD Y510 S961 S978 S983 S991 S1030 T1032 T1038 S1039 S1078 S1084 S1244 S1262 S1268 S1269 T1274 S1277 S1298 S1309 S1312 S1317 T1324 Y1325 S1326 S1343 S1346 T1350 S1358 protein RNA SCNV methylation GBM Y510 S961 S978 S983 S991 S1030 T1032 T1038 S1039 S1078 S1084 S1244 S1262 S1268 S1269 T1274 S1277 S1298 S1309 S1312 S1317 T1324 Y1325 S1326 S1343 S1346 T1350 S1358 protein RNA SCNV methylation HNSCC Y510 S961 S978 S983 S991 S1030 T1032 T1038 S1039 S1078 S1084 S1244 S1262 S1268 S1269 T1274 S1277 S1298 S1309 S1312 S1317 T1324 Y1325 S1326 S1343 S1346 T1350 S1358 protein RNA SCNV methylation LSCC Y510 S961 S978 S983 S991 S1030 T1032 T1038 S1039 S1078 S1084 S1244 S1262 S1268 S1269 T1274 S1277 S1298 S1309 S1312 S1317 T1324 Y1325 S1326 S1343 S1346 T1350 S1358 protein RNA SCNV methylation LUAD Y510 S961 S978 S983 S991 S1030 T1032 T1038 S1039 S1078 S1084 S1244 S1262 S1268 S1269 T1274 S1277 S1298 S1309 S1312 S1317 T1324 Y1325 S1326 S1343 S1346 T1350 S1358 protein RNA SCNV methylation OV Y510 S961 S978 S983 S991 S1030 T1032 T1038 S1039 S1078 S1084 S1244 S1262 S1268 S1269 T1274 S1277 S1298 S1309 S1312 S1317 T1324 Y1325 S1326 S1343 S1346 T1350 S1358 protein RNA SCNV methylation PDAC Y510 S961 S978 S983 S991 S1030 T1032 T1038 S1039 S1078 S1084 S1244 S1262 S1268 S1269 T1274 S1277 S1298 S1309 S1312 S1317 T1324 Y1325 S1326 S1343 S1346 T1350 S1358 protein RNA SCNV methylation UCEC Y510 S961 S978 S983 S991 S1030 T1032 T1038 S1039 S1078 S1084 S1244 S1262 S1268 S1269 T1274 S1277 S1298 S1309 S1312 S1317 T1324 Y1325 S1326 S1343 S1346 T1350 S1358 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y510
S961
S978
S983
S991
S1030
T1032
T1038
S1039
S1078
S1084
S1244
S1262
S1268
S1269
T1274
S1277
S1298
S1309
S1312
S1317
T1324
Y1325
S1326
S1343
S1346
T1350
S1358
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
Y510
S961
S978
S983
S991
S1030
T1032
T1038
S1039
S1078
S1084
S1244
S1262
S1268
S1269
T1274
S1277
S1298
S1309
S1312
S1317
T1324
Y1325
S1326
S1343
S1346
T1350
S1358
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.