Protein: ENSP00000491215
Gene: HNRNPU

LinkedOmicsKB © 2022-2023 Zhang Lab

HNRNPU:
heterogeneous nuclear ribonucleoprotein U

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S2______MSSSPVNVK244--------95--------30-
S3_____MSSSPVNVKK124------------------24-
S4____MSSSPVNVKKL6168------9-301415132220--5238-
S59AMEPGNGSLDLGGDS71132--10380--99-1086210899110101--105449518
S66SLDLGGDSAGRSGAG6375------90-6464591716--22116818
S187AKEAAGKSSGPTSLF5448--1919--45---68627568----7418
S188KEAAGKSSGPTSLFA7631--6563--72-171278717368--1038118
T191AGKSSGPTSLFAVTV227----------5598------
S192GKSSGPTSLFAVTVA7845--9076--81-502888819384--54198318
Y266EYIEENKYSRAKSPQ334--88--9-----54------
Showing 1 to 10 of 22 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S2______MSSSPVNVK-----------
S3_____MSSSPVNVKK-----------
S4____MSSSPVNVKKL1.8e-9----1.2e-4-3.1e-6---
S59AMEPGNGSLDLGGDS9.6e-59-7.8e-6--1.6e-132.4e-221.1e-25-7.1e-62.4e-3
S66SLDLGGDSAGRSGAG0.3-----3.6e-5---0.25-0.24
S187AKEAAGKSSGPTSLF-7.6e-18------1.9e-11-3.1e-10---0.058
S188KEAAGKSSGPTSLFA-0.029-2.9e-9----2.4e-5-3.7e-6---0.15
T191AGKSSGPTSLFAVTV-----------
S192GKSSGPTSLFAVTVA-0.37-5.7e-10---5.9e-7-5.1e-3-8.2e-4-0.90.009
Y266EYIEENKYSRAKSPQ-----------
Showing 1 to 10 of 22 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS2S3S4S59S66S187S188T191S192Y266S267S271T286T292Y293S302S330T393T530S585S799S817proteinRNASCNVmethylationCCRCCS2S3S4S59S66S187S188T191S192Y266S267S271T286T292Y293S302S330T393T530S585S799S817proteinRNASCNVmethylationCOADS2S3S4S59S66S187S188T191S192Y266S267S271T286T292Y293S302S330T393T530S585S799S817proteinRNASCNVmethylationGBMS2S3S4S59S66S187S188T191S192Y266S267S271T286T292Y293S302S330T393T530S585S799S817proteinRNASCNVmethylationHNSCCS2S3S4S59S66S187S188T191S192Y266S267S271T286T292Y293S302S330T393T530S585S799S817proteinRNASCNVmethylationLSCCS2S3S4S59S66S187S188T191S192Y266S267S271T286T292Y293S302S330T393T530S585S799S817proteinRNASCNVmethylationLUADS2S3S4S59S66S187S188T191S192Y266S267S271T286T292Y293S302S330T393T530S585S799S817proteinRNASCNVmethylationOVS2S3S4S59S66S187S188T191S192Y266S267S271T286T292Y293S302S330T393T530S585S799S817proteinRNASCNVmethylationPDACS2S3S4S59S66S187S188T191S192Y266S267S271T286T292Y293S302S330T393T530S585S799S817proteinRNASCNVmethylationUCECS2S3S4S59S66S187S188T191S192Y266S267S271T286T292Y293S302S330T393T530S585S799S817proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.