KSR1: kinase suppressor of ras 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S192 SLDARRES GSGPSTD 9 191 7 - 12 11 4 5 33 - - - 10 8 18 15 7 2 20 8 28 3 S194 DARRESGS GPSTDTL 8 253 - - 13 12 16 19 - - 20 9 10 9 17 17 34 6 45 20 6 - S197 RESGSGPS TDTLSAA 3 26 - - - - - - - - 6 3 5 5 - - - - - - 5 2 T198 ESGSGPST DTLSAAS 5 48 6 - - - - - - - - - 5 5 4 4 - - 5 1 18 - S229 AQGPRSIS VSALPAS 1 7 - - - - - - - - - - - - - - 7 - - - - - S236 SVSALPAS DSPTPSF 1 9 - - - - - - - - - - - - - - - - - - 7 2 S238 SALPASDS PTPSFSE 2 17 - - - - - - - - - - - - 4 4 8 1 - - - - T240 LPASDSPT PSFSEGL 1 8 - - - - - - - - - - - - 4 4 - - - - - - S257 TCIPLHAS GRLTPRA 2 19 - - - - - - 9 - - - 5 5 - - - - - - - - T261 LHASGRLT PRALHSF 1 35 - - - - - - 35 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S192 SLDARRES GSGPSTD - - - - - - - - - - - S194 DARRESGS GPSTDTL 0.14 - - - - - - - - 0.14 - S197 RESGSGPS TDTLSAA - - - - - - - - - - - T198 ESGSGPST DTLSAAS - - - - - - - - - - - S229 AQGPRSIS VSALPAS - - - - - - - - - - - S236 SVSALPAS DSPTPSF - - - - - - - - - - - S238 SALPASDS PTPSFSE - - - - - - - - - - - T240 LPASDSPT PSFSEGL - - - - - - - - - - - S257 TCIPLHAS GRLTPRA - - - - - - - - - - - T261 LHASGRLT PRALHSF - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S192
S194
S197
T198
S229
S236
S238
T240
S257
T261
T270
T273
T274
T288
S311
S334
S406
T425
T473
S547
S575
T577
Y580
S924
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S192 S194 S197 T198 S229 S236 S238 T240 S257 T261 T270 T273 T274 T288 S311 S334 S406 T425 T473 S547 S575 T577 Y580 S924 protein RNA SCNV methylation CCRCC S192 S194 S197 T198 S229 S236 S238 T240 S257 T261 T270 T273 T274 T288 S311 S334 S406 T425 T473 S547 S575 T577 Y580 S924 protein RNA SCNV methylation COAD S192 S194 S197 T198 S229 S236 S238 T240 S257 T261 T270 T273 T274 T288 S311 S334 S406 T425 T473 S547 S575 T577 Y580 S924 protein RNA SCNV methylation GBM S192 S194 S197 T198 S229 S236 S238 T240 S257 T261 T270 T273 T274 T288 S311 S334 S406 T425 T473 S547 S575 T577 Y580 S924 protein RNA SCNV methylation HNSCC S192 S194 S197 T198 S229 S236 S238 T240 S257 T261 T270 T273 T274 T288 S311 S334 S406 T425 T473 S547 S575 T577 Y580 S924 protein RNA SCNV methylation LSCC S192 S194 S197 T198 S229 S236 S238 T240 S257 T261 T270 T273 T274 T288 S311 S334 S406 T425 T473 S547 S575 T577 Y580 S924 protein RNA SCNV methylation LUAD S192 S194 S197 T198 S229 S236 S238 T240 S257 T261 T270 T273 T274 T288 S311 S334 S406 T425 T473 S547 S575 T577 Y580 S924 protein RNA SCNV methylation OV S192 S194 S197 T198 S229 S236 S238 T240 S257 T261 T270 T273 T274 T288 S311 S334 S406 T425 T473 S547 S575 T577 Y580 S924 protein RNA SCNV methylation PDAC S192 S194 S197 T198 S229 S236 S238 T240 S257 T261 T270 T273 T274 T288 S311 S334 S406 T425 T473 S547 S575 T577 Y580 S924 protein RNA SCNV methylation UCEC S192 S194 S197 T198 S229 S236 S238 T240 S257 T261 T270 T273 T274 T288 S311 S334 S406 T425 T473 S547 S575 T577 Y580 S924 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S192
S194
S197
T198
S229
S236
S238
T240
S257
T261
T270
T273
T274
T288
S311
S334
S406
T425
T473
S547
S575
T577
Y580
S924
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S192
S194
S197
T198
S229
S236
S238
T240
S257
T261
T270
T273
T274
T288
S311
S334
S406
T425
T473
S547
S575
T577
Y580
S924
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.