INPP5F: inositol polyphosphate-5-phosphatase F
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4xuu chain A
4xuu chain B
4xuu chain C
4xuu chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S123 KPEKIIPS PDDSKFL 7 631 - - 48 37 - - 99 - 31 22 10 10 79 71 - - 78 33 95 18 S257 ESSDDEKS SPETPPQ 2 26 - - - - - - 19 - - - - - - - - - - - 5 2 S258 SSDDEKSS PETPPQE 2 16 - - 4 4 - - - - - - - - - - - - - - 6 2 T261 DEKSSPET PPQESTC 3 53 - - - - - - 18 - - - 15 14 - - - - - - 6 - S668 VNQYQRLS LENLEKI 7 895 - - 66 60 - - 90 - 81 44 98 90 88 80 - - 68 28 84 18 S769 IRSQNQGS LAQGKNF 1 18 - - - - - - 18 - - - - - - - - - - - - - S783 FLMSKFSS LNQKVKQ 4 64 - - 8 6 - - 35 - 7 2 - - - - - - - - 6 - S793 QKVKQTKS NVNIGNL 7 137 - - 8 8 - - 18 - 5 3 24 21 4 4 - - 3 2 28 9 S827 LKVNLWKS DSSLETM 7 608 - - 9 8 - - 90 - 34 21 74 69 45 39 - - 82 36 83 18 S829 VNLWKSDS SLETMEN 6 180 - - 67 45 - - - - 6 4 20 17 4 4 - - 5 2 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S123 KPEKIIPS PDDSKFL -0.02 - -0.013 - - -0.94 - -0.034 - -6.1e-4 3.8e-3 S257 ESSDDEKS SPETPPQ - - - - - - - - - - - S258 SSDDEKSS PETPPQE - - - - - - - - - - - T261 DEKSSPET PPQESTC - - - - - - - - - - - S668 VNQYQRLS LENLEKI -0.47 - 0.4 - - 0.17 -0.33 -2.6e-5 - 0.13 1.2e-3 S769 IRSQNQGS LAQGKNF - - - - - - - - - - - S783 FLMSKFSS LNQKVKQ - - - - - - - - - - - S793 QKVKQTKS NVNIGNL 0.13 - - - - - 0.13 - - - - S827 LKVNLWKS DSSLETM 1.1e-16 - - - - 0.085 1e-15 5.3e-10 - -0.047 4.6e-6 S829 VNLWKSDS SLETMEN 4.8e-10 - 1.8e-7 - - - 3.4e-4 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S123
S257
S258
T261
S668
S769
S783
S793
S827
S829
S830
T833
S869
S878
S881
S907
S909
S910
S935
S940
S942
T950
S981
S985
T1039
S1069
S1103
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S123 S257 S258 T261 S668 S769 S783 S793 S827 S829 S830 T833 S869 S878 S881 S907 S909 S910 S935 S940 S942 T950 S981 S985 T1039 S1069 S1103 protein RNA SCNV methylation CCRCC S123 S257 S258 T261 S668 S769 S783 S793 S827 S829 S830 T833 S869 S878 S881 S907 S909 S910 S935 S940 S942 T950 S981 S985 T1039 S1069 S1103 protein RNA SCNV methylation COAD S123 S257 S258 T261 S668 S769 S783 S793 S827 S829 S830 T833 S869 S878 S881 S907 S909 S910 S935 S940 S942 T950 S981 S985 T1039 S1069 S1103 protein RNA SCNV methylation GBM S123 S257 S258 T261 S668 S769 S783 S793 S827 S829 S830 T833 S869 S878 S881 S907 S909 S910 S935 S940 S942 T950 S981 S985 T1039 S1069 S1103 protein RNA SCNV methylation HNSCC S123 S257 S258 T261 S668 S769 S783 S793 S827 S829 S830 T833 S869 S878 S881 S907 S909 S910 S935 S940 S942 T950 S981 S985 T1039 S1069 S1103 protein RNA SCNV methylation LSCC S123 S257 S258 T261 S668 S769 S783 S793 S827 S829 S830 T833 S869 S878 S881 S907 S909 S910 S935 S940 S942 T950 S981 S985 T1039 S1069 S1103 protein RNA SCNV methylation LUAD S123 S257 S258 T261 S668 S769 S783 S793 S827 S829 S830 T833 S869 S878 S881 S907 S909 S910 S935 S940 S942 T950 S981 S985 T1039 S1069 S1103 protein RNA SCNV methylation OV S123 S257 S258 T261 S668 S769 S783 S793 S827 S829 S830 T833 S869 S878 S881 S907 S909 S910 S935 S940 S942 T950 S981 S985 T1039 S1069 S1103 protein RNA SCNV methylation PDAC S123 S257 S258 T261 S668 S769 S783 S793 S827 S829 S830 T833 S869 S878 S881 S907 S909 S910 S935 S940 S942 T950 S981 S985 T1039 S1069 S1103 protein RNA SCNV methylation UCEC S123 S257 S258 T261 S668 S769 S783 S793 S827 S829 S830 T833 S869 S878 S881 S907 S909 S910 S935 S940 S942 T950 S981 S985 T1039 S1069 S1103 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S123
S257
S258
T261
S668
S769
S783
S793
S827
S829
S830
T833
S869
S878
S881
S907
S909
S910
S935
S940
S942
T950
S981
S985
T1039
S1069
S1103
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S123
S257
S258
T261
S668
S769
S783
S793
S827
S829
S830
T833
S869
S878
S881
S907
S909
S910
S935
S940
S942
T950
S981
S985
T1039
S1069
S1103
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.