EIF4A3: eukaryotic translation initiation factor 4A3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2hxy chain A
2hxy chain B
2hxy chain C
2hxy chain D
2hyi chain C
2hyi chain I
2j0q chain A
2j0q chain B
2j0s chain A
2j0u chain A
2j0u chain B
2xb2 chain A
2xb2 chain X
3ex7 chain C
3ex7 chain H
4c9b chain A
5mqf chain p
5xjc chain u
5yzg chain u
6icz chain u
6qdv chain 7
6yvh chain H
6yvh chain J
6yvh chain K
6yvh chain L
7a5p chain y
7w59 chain u
7w5a chain u
7w5b chain u
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T163 GQHVVAGT PGRVFDM 7 575 - - 31 23 - - - - 108 62 25 24 79 73 71 14 12 5 39 9
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T163 GQHVVAGT PGRVFDM 1.1e-8 - -0.48 - - 0.095 5.9e-7 5.4e-5 5.1e-3 - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
T163
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T163 protein RNA SCNV methylation CCRCC T163 protein RNA SCNV methylation COAD T163 protein RNA SCNV methylation GBM T163 protein RNA SCNV methylation HNSCC T163 protein RNA SCNV methylation LSCC T163 protein RNA SCNV methylation LUAD T163 protein RNA SCNV methylation OV T163 protein RNA SCNV methylation PDAC T163 protein RNA SCNV methylation UCEC T163 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T163
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T163
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.