RIN2: Ras and Rab interactor 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y62 VRHKDGGY SEEEDVK 1 16 - - 8 8 - - - - - - - - - - - - - - - - S63 RHKDGGYS EEEDVKT 9 962 41 - 81 60 24 21 63 - 97 56 79 72 89 81 - - 91 38 51 18 S79 ARDSGYDS LSNRLSI 10 777 53 - 25 16 44 37 17 - 63 36 39 36 91 85 56 12 85 34 35 13 S218 FWSSPADS KPPNLPP 4 68 7 - 5 4 - - - - - - 10 8 18 16 - - - - - - S231 PPPHRPLS SDGVCPA 1 10 - - - - - - - - 6 4 - - - - - - - - - - S251 CLINGVHS IKTRTPS 4 112 62 - 11 11 - - - - - - 10 10 4 4 - - - - - - T256 VHSIKTRT PSELECS 1 5 - - - - - - - - - - - - - - - - 3 2 - - S258 SIKTRTPS ELECSQT 5 131 9 - - - 16 11 - - 22 13 14 12 18 16 - - - - - - T265 SELECSQT NGALCFI 1 8 - - - - - - - - 5 3 - - - - - - - - - - S281 PLFLKVHS QDLSGGL 7 186 22 - 36 27 - - 18 - - - 5 4 26 24 16 2 - - 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y62 VRHKDGGY SEEEDVK - - - - - - - - - - - S63 RHKDGGYS EEEDVKT -7.7e-7 - 1.2e-6 0.45 - 0.92 -5.3e-14 -9.8e-7 - -0.086 -3.3e-6 S79 ARDSGYDS LSNRLSI 2.7e-10 - 6.8e-8 1.0e-6 - 3.4e-5 -0.038 0.046 0.82 1.3e-11 -4.9e-4 S218 FWSSPADS KPPNLPP - - - - - - - - - - - S231 PPPHRPLS SDGVCPA - - - - - - - - - - - S251 CLINGVHS IKTRTPS - - - - - - - - - - - T256 VHSIKTRT PSELECS - - - - - - - - - - - S258 SIKTRTPS ELECSQT 0.11 - - - - 0.11 - - - - - T265 SELECSQT NGALCFI - - - - - - - - - - - S281 PLFLKVHS QDLSGGL 2.9e-8 - 0.001 - - - - 5.0e-6 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y62
S63
S79
S218
S231
S251
T256
S258
T265
S281
T304
S306
S318
S322
T332
S333
S366
S395
T457
S459
S460
Y464
S468
T472
S484
S485
S486
S501
T767
T780
S783
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y62 S63 S79 S218 S231 S251 T256 S258 T265 S281 T304 S306 S318 S322 T332 S333 S366 S395 T457 S459 S460 Y464 S468 T472 S484 S485 S486 S501 T767 T780 S783 protein RNA SCNV methylation CCRCC Y62 S63 S79 S218 S231 S251 T256 S258 T265 S281 T304 S306 S318 S322 T332 S333 S366 S395 T457 S459 S460 Y464 S468 T472 S484 S485 S486 S501 T767 T780 S783 protein RNA SCNV methylation COAD Y62 S63 S79 S218 S231 S251 T256 S258 T265 S281 T304 S306 S318 S322 T332 S333 S366 S395 T457 S459 S460 Y464 S468 T472 S484 S485 S486 S501 T767 T780 S783 protein RNA SCNV methylation GBM Y62 S63 S79 S218 S231 S251 T256 S258 T265 S281 T304 S306 S318 S322 T332 S333 S366 S395 T457 S459 S460 Y464 S468 T472 S484 S485 S486 S501 T767 T780 S783 protein RNA SCNV methylation HNSCC Y62 S63 S79 S218 S231 S251 T256 S258 T265 S281 T304 S306 S318 S322 T332 S333 S366 S395 T457 S459 S460 Y464 S468 T472 S484 S485 S486 S501 T767 T780 S783 protein RNA SCNV methylation LSCC Y62 S63 S79 S218 S231 S251 T256 S258 T265 S281 T304 S306 S318 S322 T332 S333 S366 S395 T457 S459 S460 Y464 S468 T472 S484 S485 S486 S501 T767 T780 S783 protein RNA SCNV methylation LUAD Y62 S63 S79 S218 S231 S251 T256 S258 T265 S281 T304 S306 S318 S322 T332 S333 S366 S395 T457 S459 S460 Y464 S468 T472 S484 S485 S486 S501 T767 T780 S783 protein RNA SCNV methylation OV Y62 S63 S79 S218 S231 S251 T256 S258 T265 S281 T304 S306 S318 S322 T332 S333 S366 S395 T457 S459 S460 Y464 S468 T472 S484 S485 S486 S501 T767 T780 S783 protein RNA SCNV methylation PDAC Y62 S63 S79 S218 S231 S251 T256 S258 T265 S281 T304 S306 S318 S322 T332 S333 S366 S395 T457 S459 S460 Y464 S468 T472 S484 S485 S486 S501 T767 T780 S783 protein RNA SCNV methylation UCEC Y62 S63 S79 S218 S231 S251 T256 S258 T265 S281 T304 S306 S318 S322 T332 S333 S366 S395 T457 S459 S460 Y464 S468 T472 S484 S485 S486 S501 T767 T780 S783 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y62
S63
S79
S218
S231
S251
T256
S258
T265
S281
T304
S306
S318
S322
T332
S333
S366
S395
T457
S459
S460
Y464
S468
T472
S484
S485
S486
S501
T767
T780
S783
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
Y62
S63
S79
S218
S231
S251
T256
S258
T265
S281
T304
S306
S318
S322
T332
S333
S366
S395
T457
S459
S460
Y464
S468
T472
S484
S485
S486
S501
T767
T780
S783
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.