MYD88: MYD88 innate immune signal transduction adaptor
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2js7 chain A
2z5v chain A
3mop chain A
3mop chain B
3mop chain C
3mop chain D
3mop chain E
3mop chain F
4dom chain A
4eo7 chain A
6i3n chain A
6i3n chain B
6i3n chain C
6i3n chain D
6i3n chain E
6i3n chain F
6i3n chain G
6i3n chain H
6i3n chain I
6i3n chain J
6i3n chain K
6i3n chain L
6i3n chain M
7beq chain A
7ber chain A
7l6w chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S244 TKFALSLS PGAHQKR 5 230 15 - - - 11 7 45 - 90 54 - - - - 6 2 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S244 TKFALSLS PGAHQKR 4.3e-5 - - - - 4.3e-5 - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S244
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S244 protein RNA SCNV methylation CCRCC S244 protein RNA SCNV methylation COAD S244 protein RNA SCNV methylation GBM S244 protein RNA SCNV methylation HNSCC S244 protein RNA SCNV methylation LSCC S244 protein RNA SCNV methylation LUAD S244 protein RNA SCNV methylation OV S244 protein RNA SCNV methylation PDAC S244 protein RNA SCNV methylation UCEC S244 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S244
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S244
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.