Protein: ENSP00000498586
Gene: SEPTIN1

LinkedOmicsKB © 2022-2023 Zhang Lab

SEPTIN1:
septin 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S206YQFPECDSDEDEDFK91276113-10380352881-1086210899110101--100438718
S248PVRGRRYSWGTVEVE968414-1312848681-643859541717--8934175
T251GRRYSWGTVEVENPH812817-1616279-5410888--135--
S312RASRSKLSRQSATEI5567---72------1213--726-
S315RSKLSRQSATEIPLP101402113-103809710036-10862108991101013811105446918
T317KLSRQSATEIPLPML71759-248----35211091311--1898-
Showing 1 to 6 of 6 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S206YQFPECDSDEDEDFK0.047-5.2e-5-3.1e-3--0.180.0170.046-0.15-0.74
S248PVRGRRYSWGTVEVE-0.84---4.7e-10-0.240.44--1.1e-4-
T251GRRYSWGTVEVENPH-----------
S312RASRSKLSRQSATEI-----------
S315RSKLSRQSATEIPLP-3.9e-9-4.2e-16-3.4e-12--0.059-9e-10-3.8e-4-0.14-0.49-4.5e-5
T317KLSRQSATEIPLPML-0.35-----0.35-----
Showing 1 to 6 of 6 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS206S248T251S312S315T317proteinRNASCNVmethylationCCRCCS206S248T251S312S315T317proteinRNASCNVmethylationCOADS206S248T251S312S315T317proteinRNASCNVmethylationGBMS206S248T251S312S315T317proteinRNASCNVmethylationHNSCCS206S248T251S312S315T317proteinRNASCNVmethylationLSCCS206S248T251S312S315T317proteinRNASCNVmethylationLUADS206S248T251S312S315T317proteinRNASCNVmethylationOVS206S248T251S312S315T317proteinRNASCNVmethylationPDACS206S248T251S312S315T317proteinRNASCNVmethylationUCECS206S248T251S312S315T317proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.