CDC42: cell division cycle 42
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1a4r chain A
1a4r chain B
1aje chain A
1am4 chain D
1am4 chain E
1am4 chain F
1an0 chain A
1an0 chain B
1cee chain A
1cf4 chain A
1doa chain A
1e0a chain A
1ees chain A
1grn chain A
1gzs chain A
1gzs chain C
1ki1 chain A
1ki1 chain C
1kz7 chain B
1kz7 chain D
1kzg chain B
1kzg chain D
1nf3 chain A
1nf3 chain B
2ase chain A
2dfk chain B
2dfk chain D
2kb0 chain A
2ngr chain A
2odb chain A
2qrz chain A
2qrz chain B
2wm9 chain B
2wmn chain B
2wmo chain B
3gcg chain A
3qbv chain A
3qbv chain C
3vhl chain B
4did chain A
4itr chain C
4itr chain D
4js0 chain A
4yc7 chain A
4ydh chain B
4ydh chain D
5cjp chain A
5cjp chain B
5cjp chain C
5cjp chain D
5fi1 chain B
5upk chain C
5upl chain B
6aj4 chain B
6aj4 chain D
6aj4 chain F
6aj4 chain H
6ajl chain B
6ajl chain D
6ajl chain F
6ajl chain H
6siu chain C
6siu chain D
6sup chain A
6tky chain C
6tky chain D
6tkz chain C
6tkz chain D
7s0y chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T138 KNKQKPIT PETAEKL 5 180 - - 23 15 - - 9 - 22 15 - - 37 36 - - 17 6 - - T141 QKPITPET AEKLARD 2 24 - - - - - - 18 - - - - - - - - - 5 1 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T138 KNKQKPIT PETAEKL 0.93 - 2.8e-5 - - 0.87 - -2.6e-5 - - - T141 QKPITPET AEKLARD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T138
T141
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T138 T141 protein RNA SCNV methylation CCRCC T138 T141 protein RNA SCNV methylation COAD T138 T141 protein RNA SCNV methylation GBM T138 T141 protein RNA SCNV methylation HNSCC T138 T141 protein RNA SCNV methylation LSCC T138 T141 protein RNA SCNV methylation LUAD T138 T141 protein RNA SCNV methylation OV T138 T141 protein RNA SCNV methylation PDAC T138 T141 protein RNA SCNV methylation UCEC T138 T141 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T138
T141
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T138
T141
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.