Protein: ENSP00000053243
Gene: TNFRSF17

LinkedOmicsKB © 2022-2023 Zhang Lab

TNFRSF17:
TNF receptor superfamily member 17

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S94DEFKNTGSGLLGMAN61727-44612----34303130--104--
S173KSLPAALSATEIEKS438--------6354----9452
T175LPAALSATEIEKSIS19------------45------
Showing 1 to 3 of 3 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S94DEFKNTGSGLLGMAN8.9e-4-----0.371.5e-4---
S173KSLPAALSATEIEKS-----------
T175LPAALSATEIEKSIS-----------
Showing 1 to 3 of 3 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
xcell: B cell plasmaS947.7e-8-----1.3e-61.4e-5-0.89-
xcell: T cell CD8+S945.2e-6-----3.3e-41.1e-4-0.66-
xcell: T cell CD8+ central memoryS948.0e-6-----2.8e-42.7e-4-0.65-
xcell: T cell CD4+ effector memoryS943.2e-5-----2.4e-40.011-0.33-
xcell: Class-switched memory B cellS944.3e-5-----4.5e-51.3e-4--0.41-
xcell: B cellS947.7e-5-----1.2e-55.7e-4--0.33-
cibersort: T cell CD4+ memory restingS942.0e-4-----5.4e-30.046-0.096-
cibersort: B cell plasmaS944.1e-4-----0.0150.047-0.088-
xcell: T cell CD4+ memoryS944.1e-4-----7.6e-50.018--0.84-
xcell: immune scoreS944.9e-4-----1.3e-52.2e-3--0.17-
Showing 1 to 10 of 774 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS94S173T175proteinRNASCNVmethylationCCRCCS94S173T175proteinRNASCNVmethylationCOADS94S173T175proteinRNASCNVmethylationGBMS94S173T175proteinRNASCNVmethylationHNSCCS94S173T175proteinRNASCNVmethylationLSCCS94S173T175proteinRNASCNVmethylationLUADS94S173T175proteinRNASCNVmethylationOVS94S173T175proteinRNASCNVmethylationPDACS94S173T175proteinRNASCNVmethylationUCECS94S173T175proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
MAP4K1S947.8e-10-----2.6e-53.5e-5-0.021-
LCKS945.4e-8-----4.7e-52.9e-4---
PDK1S942.8e-7-----4.7e-32.2e-6-0.18-
PRKACBS941.3e-5-----5.2e-70.25-1-
JAK2S942.9e-5-----3.9e-40.018---
ZAP70S943.1e-5-----6.7e-57.9e-5--0.47-
LRRK1S943.7e-5-----3.2e-60.24---
PRKD2S946.4e-5-----5.7e-57.9e-3-0.81-
GRK6S942.6e-4-----6.9e-52.4e-3--0.49-
CAMK4S943.3e-4-----0.0070.033-0.17-
Showing 1 to 10 of 1614 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
PTPN11S94-1.6e-3------0.042-0.36--0.012-
PTPRFS94-7.4e-3------0.011-0.017-0.76-
NT5C3BS94-0.012------5.7e-3-0.093-0.92-
PPP1CBS94-0.02------1.1e-3-0.2-0.61-
PTPN3S94-0.021------0.15-0.07---
MTMR2S94-0.028------0.0180.72--0.073-
PPP4CS94-0.03------0.021-0.18--0.89-
PLPP6S94-0.032------0.58-0.36--0.024-
OCRLS94-0.038------0.12-7.3e-3-0.51-
PPM1HS94-0.039------0.36-0.034--0.58-
Showing 1 to 10 of 720 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.