Protein: ENSP00000261254
Gene: CCND2

LinkedOmicsKB © 2022-2023 Zhang Lab

CCND2:
cyclin D2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S271DQRDGSKSEDELDQA4170----252064-64----438----
S279EDELDQASTPTDVRD5132--88117--6328261916------
T280DELDQASTPTDVRDI910159-8765545499-905393854037--96409518
Showing 1 to 3 of 3 rows

Tumor and normal comparison

Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S271DQRDGSKSEDELDQA-0.41---0.41-------
S279EDELDQASTPTDVRD0.32-----0.32----
T280DELDQASTPTDVRDI-0.012--0.240.021-3.8e-3-3.9e-3-0.002--7.1e-4-0.17
Showing 1 to 3 of 3 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

Loading, please wait
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
KINASE-PSP_GSK3BT2805.1e-6---1.1e-40.43-0.21--0.0461.6e-6
HALLMARK_HEDGEHOG_SIGNALINGT2807.5e-5-0.560.420.290.156.7e-6-0.098-0.0140.045
HALLMARK_PANCREAS_BETA_CELLST2801.1e-4-0.910.930.10.0820.0250.41-0.0110.078
HALLMARK_UV_RESPONSE_DNT2803.3e-4-0.130.31-0.0880.283.6e-30.74-0.0140.011
xcell: Hematopoietic stem cellT2805.6e-4-0.170.130.27-0.190.510.76-5.1e-48.2e-3
xcell: stroma scoreT2806.3e-4-0.0430.27-0.190.990.0270.68-0.0391.5e-3
xcell: Cancer associated fibroblastT2801.2e-3-0.0680.25-0.0340.750.0480.65-0.0473.4e-4
xcell: T cell CD4+ naiveT2801.3e-3-0.090.190.88-0.898.5e-30.12--0.590.016
HALLMARK_WNT_BETA_CATENIN_SIGNALINGT2801.8e-3-0.0320.450.590.510.015-0.096-0.0420.052
HALLMARK_NOTCH_SIGNALINGT2802.1e-3-0.0980.460.610.970.16-0.68-0.0397.5e-3
Showing 1 to 10 of 774 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS271S279T280proteinRNASCNVmethylationCCRCCS271S279T280proteinRNASCNVmethylationCOADS271S279T280proteinRNASCNVmethylationGBMS271S279T280proteinRNASCNVmethylationHNSCCS271S279T280proteinRNASCNVmethylationLSCCS271S279T280proteinRNASCNVmethylationLUADS271S279T280proteinRNASCNVmethylationOVS271S279T280proteinRNASCNVmethylationPDACS271S279T280proteinRNASCNVmethylationUCECS271S279T280proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

Loading, please wait
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.