Protein: ENSP00000261842
Gene: AP4E1

LinkedOmicsKB © 2022-2023 Zhang Lab

AP4E1:
adaptor related protein complex 4 subunit epsilon 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S676SGFTGRQSPAGISLG1087552-4440252045-101609889706614362234716
S681RQSPAGISLGSDVSG110----------55--------
S684PAGISLGSDVSGNSA3369---------55------134
S687ISLGSDVSGNSAETG248------------44----364
S690GSDVSGNSAETGLKE346------------54--52246
T698AETGLKETNSLKLEG18--------------53----
S700TGLKETNSLKLEGIK631397---------3836585313432-9
S847DKELKKFSLTSELLD447----5418---------83-9
T849ELKKFSLTSELLDSE15----------------32--
S850LKKFSLTSELLDSES16----------------51--
Showing 1 to 10 of 11 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S676SGFTGRQSPAGISLG0.015-0.98-2.2e-4--1.6e-55.0e-65.2e-9-0.0880.021
S681RQSPAGISLGSDVSG-----------
S684PAGISLGSDVSGNSA-----------
S687ISLGSDVSGNSAETG-----------
S690GSDVSGNSAETGLKE-----------
T698AETGLKETNSLKLEG-----------
S700TGLKETNSLKLEGIK2.2e-12-----0.0013e-11---
S847DKELKKFSLTSELLD-----------
T849ELKKFSLTSELLDSE-----------
S850LKKFSLTSELLDSES-----------
Showing 1 to 10 of 11 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS676S681S684S687S690T698S700S847T849S850S857proteinRNASCNVmethylationCCRCCS676S681S684S687S690T698S700S847T849S850S857proteinRNASCNVmethylationCOADS676S681S684S687S690T698S700S847T849S850S857proteinRNASCNVmethylationGBMS676S681S684S687S690T698S700S847T849S850S857proteinRNASCNVmethylationHNSCCS676S681S684S687S690T698S700S847T849S850S857proteinRNASCNVmethylationLSCCS676S681S684S687S690T698S700S847T849S850S857proteinRNASCNVmethylationLUADS676S681S684S687S690T698S700S847T849S850S857proteinRNASCNVmethylationOVS676S681S684S687S690T698S700S847T849S850S857proteinRNASCNVmethylationPDACS676S681S684S687S690T698S700S847T849S850S857proteinRNASCNVmethylationUCECS676S681S684S687S690T698S700S847T849S850S857proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.