Protein: ENSP00000262461
Gene: SLC12A2

LinkedOmicsKB © 2022-2023 Zhang Lab

SLC12A2:
solute carrier family 12 member 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S23AGVGETPSAAALAAA10105764-1412969945-97569891837722474337616
S41LPGTAVPSVPEDAAP215----54------------6-
S50PEDAAPASRDGGGVR19----45--------------
T75LGRPLGPTPSQSRFQ932541-34243933--29171010222015394132
S77RPLGPTPSQSRFQVD101463105-69519710099-1086210898110101831999419518
S123TPADGEASGESEPAK983553-449710054-895358523228--93406018
S126DGEASGESEPAKGSE979038-2020232246-1076249449081--91354616
S132ESEPAKGSEEAKGRF2113----5940------------113
T212TNTYYLRTFGHNTMD3134----4958--54----153----
T217LRTFGHNTMDAVPRI101137104-2012657881-10862104958780831963263416
Showing 1 to 10 of 20 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S23AGVGETPSAAALAAA0.11--0.78--1.7e-3-0.480.46-2e-80.29
S41LPGTAVPSVPEDAAP-----------
S50PEDAAPASRDGGGVR-----------
T75LGRPLGPTPSQSRFQ0.58--1.7e-30.04--0.8-0.015---
S77RPLGPTPSQSRFQVD9.3e-12--7.6e-101.1e-6--0.131.8e-162.7e-112.3e-30.0130.097
S123TPADGEASGESEPAK2.9e-13--2e-14--7.6e-35.6e-41.6e-4-0.468.3e-7
S126DGEASGESEPAKGSE5.1e-6--1.1e-59.2e-7--0.0664.2e-61.3e-11--0.312.3e-3
S132ESEPAKGSEEAKGRF5.8e-9--5.8e-9-------
T212TNTYYLRTFGHNTMD-6.2e-5---6.2e-5-------
T217LRTFGHNTMDAVPRI-7.3e-20-0.14-8.7e-10--6.6e-3-5.2e-12-1.4e-7-0.013-0.44-2.4e-3
Showing 1 to 10 of 20 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS23S41S50T75S77S123S126S132T212T217T230S242S265T266T268S939S940S944T986S994proteinRNASCNVmethylationCCRCCS23S41S50T75S77S123S126S132T212T217T230S242S265T266T268S939S940S944T986S994proteinRNASCNVmethylationCOADS23S41S50T75S77S123S126S132T212T217T230S242S265T266T268S939S940S944T986S994proteinRNASCNVmethylationGBMS23S41S50T75S77S123S126S132T212T217T230S242S265T266T268S939S940S944T986S994proteinRNASCNVmethylationHNSCCS23S41S50T75S77S123S126S132T212T217T230S242S265T266T268S939S940S944T986S994proteinRNASCNVmethylationLSCCS23S41S50T75S77S123S126S132T212T217T230S242S265T266T268S939S940S944T986S994proteinRNASCNVmethylationLUADS23S41S50T75S77S123S126S132T212T217T230S242S265T266T268S939S940S944T986S994proteinRNASCNVmethylationOVS23S41S50T75S77S123S126S132T212T217T230S242S265T266T268S939S940S944T986S994proteinRNASCNVmethylationPDACS23S41S50T75S77S123S126S132T212T217T230S242S265T266T268S939S940S944T986S994proteinRNASCNVmethylationUCECS23S41S50T75S77S123S126S132T212T217T230S242S265T266T268S939S940S944T986S994proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.