Protein: ENSP00000294383
Gene: USP24

LinkedOmicsKB © 2022-2023 Zhang Lab

USP24:
ubiquitin specific peptidase 24

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y50NERPGLDYGGYEPMD18------------44------
S58GGYEPMDSGGGPSPG4328-33------5544------
S63MDSGGGPSPGPGGGP1082122-3734625563-573383778376628233124
S84DGGGGGPSRGGSTGG4194--134----6469641816------
S88GGPSRGGSTGGGGGF8235--446364---991314215125597
T89GPSRGGSTGGGGGFD822614-3224--17-1173531181714321--
S117NDENGNCSGEGIEFP3147--2820------2423------439
S622KKDGFKSSQLNNPQF115--87----------------
S914TVATSVQSPYRSTKL292------46-----------424
T1039VKTSGSGTPSGSSAD361------9---44------359
Showing 1 to 10 of 51 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y50NERPGLDYGGYEPMD-----------
S58GGYEPMDSGGGPSPG-----------
S63MDSGGGPSPGPGGGP-3.2e-16--0.018-0.16--6.4e-13-1.2e-9-0.24--0.075-
S84DGGGGGPSRGGSTGG-3.6e-9------3.6e-9----
S88GGPSRGGSTGGGGGF-----------
T89GPSRGGSTGGGGGFD-0.29-8.7e-4----1.4e-6----
S117NDENGNCSGEGIEFP-2.0e-5--0.19----2.2e-6----
S622KKDGFKSSQLNNPQF-----------
S914TVATSVQSPYRSTKL-----------
T1039VKTSGSGTPSGSSAD-----------
Showing 1 to 10 of 51 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAY50S58S63S84S88T89S117S622S914T1039S1041S1132S1136S1138S1139S1141S1281S1285T1289S1299S1305S1360S1371S1372S1373S1375S1378S1379S1381S1612S1854S1925S1935S1943S2047S2057S2069S2072S2073S2077S2080S2081T2240S2330T2559S2561T2565S2582S2587S2588S2604proteinRNASCNVmethylationCCRCCY50S58S63S84S88T89S117S622S914T1039S1041S1132S1136S1138S1139S1141S1281S1285T1289S1299S1305S1360S1371S1372S1373S1375S1378S1379S1381S1612S1854S1925S1935S1943S2047S2057S2069S2072S2073S2077S2080S2081T2240S2330T2559S2561T2565S2582S2587S2588S2604proteinRNASCNVmethylationCOADY50S58S63S84S88T89S117S622S914T1039S1041S1132S1136S1138S1139S1141S1281S1285T1289S1299S1305S1360S1371S1372S1373S1375S1378S1379S1381S1612S1854S1925S1935S1943S2047S2057S2069S2072S2073S2077S2080S2081T2240S2330T2559S2561T2565S2582S2587S2588S2604proteinRNASCNVmethylationGBMY50S58S63S84S88T89S117S622S914T1039S1041S1132S1136S1138S1139S1141S1281S1285T1289S1299S1305S1360S1371S1372S1373S1375S1378S1379S1381S1612S1854S1925S1935S1943S2047S2057S2069S2072S2073S2077S2080S2081T2240S2330T2559S2561T2565S2582S2587S2588S2604proteinRNASCNVmethylationHNSCCY50S58S63S84S88T89S117S622S914T1039S1041S1132S1136S1138S1139S1141S1281S1285T1289S1299S1305S1360S1371S1372S1373S1375S1378S1379S1381S1612S1854S1925S1935S1943S2047S2057S2069S2072S2073S2077S2080S2081T2240S2330T2559S2561T2565S2582S2587S2588S2604proteinRNASCNVmethylationLSCCY50S58S63S84S88T89S117S622S914T1039S1041S1132S1136S1138S1139S1141S1281S1285T1289S1299S1305S1360S1371S1372S1373S1375S1378S1379S1381S1612S1854S1925S1935S1943S2047S2057S2069S2072S2073S2077S2080S2081T2240S2330T2559S2561T2565S2582S2587S2588S2604proteinRNASCNVmethylationLUADY50S58S63S84S88T89S117S622S914T1039S1041S1132S1136S1138S1139S1141S1281S1285T1289S1299S1305S1360S1371S1372S1373S1375S1378S1379S1381S1612S1854S1925S1935S1943S2047S2057S2069S2072S2073S2077S2080S2081T2240S2330T2559S2561T2565S2582S2587S2588S2604proteinRNASCNVmethylationOVY50S58S63S84S88T89S117S622S914T1039S1041S1132S1136S1138S1139S1141S1281S1285T1289S1299S1305S1360S1371S1372S1373S1375S1378S1379S1381S1612S1854S1925S1935S1943S2047S2057S2069S2072S2073S2077S2080S2081T2240S2330T2559S2561T2565S2582S2587S2588S2604proteinRNASCNVmethylationPDACY50S58S63S84S88T89S117S622S914T1039S1041S1132S1136S1138S1139S1141S1281S1285T1289S1299S1305S1360S1371S1372S1373S1375S1378S1379S1381S1612S1854S1925S1935S1943S2047S2057S2069S2072S2073S2077S2080S2081T2240S2330T2559S2561T2565S2582S2587S2588S2604proteinRNASCNVmethylationUCECY50S58S63S84S88T89S117S622S914T1039S1041S1132S1136S1138S1139S1141S1281S1285T1289S1299S1305S1360S1371S1372S1373S1375S1378S1379S1381S1612S1854S1925S1935S1943S2047S2057S2069S2072S2073S2077S2080S2081T2240S2330T2559S2561T2565S2582S2587S2588S2604proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.