DAB2: DAB adaptor protein 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2lsw chain A
6o5o chain A
6o5o chain B
6ovf chain A
6ovf chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T7 _MSNEVET SATNGQP 1 10 - - - - - - - - 6 4 - - - - - - - - - - S8 MSNEVETS ATNGQPD 1 10 - - - - - - - - 6 4 - - - - - - - - - - S193 SKAVENGS EALMILD 7 580 79 - 91 69 - - - - 32 20 68 63 52 50 - - 25 11 9 11 S220 MDLFGDMS TPPDLNS 3 31 6 - 8 8 - - 9 - - - - - - - - - - - - - T221 DLFGDMST PPDLNSP 10 388 24 - 73 52 24 21 37 - 26 18 5 5 12 12 6 1 13 7 37 15 S227 STPPDLNS PTESKDI 10 1151 30 - 34 31 84 77 99 - 86 49 83 76 85 75 66 17 103 43 95 18 T229 PPDLNSPT ESKDILL 1 33 - - - - - - - - - - - - - - - - - - 31 2 S231 DLNSPTES KDILLVD 1 9 - - - - - - - - - - - - - - - - 7 2 - - S241 ILLVDLNS EIDTNQN 4 242 8 - 56 46 - - - - - - 20 19 48 45 - - - - - - S316 SSFDSLKS PDQKKEN 1 49 - - - - - - - - - - - - - - 40 9 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T7 _MSNEVET SATNGQP - - - - - - - - - - - S8 MSNEVETS ATNGQPD - - - - - - - - - - - S193 SKAVENGS EALMILD -1.6e-28 - -3.7e-14 - - -1.8e-3 -3.7e-15 -2.3e-11 - 0.64 - S220 MDLFGDMS TPPDLNS - - - - - - - - - - - T221 DLFGDMST PPDLNSP -0.61 - 4.9e-5 -0.55 - 0.77 - - - - -1.9e-6 S227 STPPDLNS PTESKDI -1.9e-22 - 2.7e-3 -0.13 - -1.0e-5 -1.6e-18 -3.9e-11 -1.5e-4 -0.55 -9.6e-7 T229 PPDLNSPT ESKDILL - - - - - - - - - - - S231 DLNSPTES KDILLVD - - - - - - - - - - - S241 ILLVDLNS EIDTNQN -1.5e-3 - 1.9e-4 - - - -5.7e-6 -2.5e-6 - - - S316 SSFDSLKS PDQKKEN - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T7
S8
S193
S220
T221
S227
T229
S231
S241
S316
S326
S327
S328
T329
S332
Y342
S367
S390
S393
S394
S401
S407
S423
S427
S448
S449
S456
S464
S467
S471
T473
T477
S633
S634
T674
S675
S676
T678
S680
S684
S723
T727
S729
T730
S742
S749
S753
S757
S758
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T7 S8 S193 S220 T221 S227 T229 S231 S241 S316 S326 S327 S328 T329 S332 Y342 S367 S390 S393 S394 S401 S407 S423 S427 S448 S449 S456 S464 S467 S471 T473 T477 S633 S634 T674 S675 S676 T678 S680 S684 S723 T727 S729 T730 S742 S749 S753 S757 S758 protein RNA SCNV methylation CCRCC T7 S8 S193 S220 T221 S227 T229 S231 S241 S316 S326 S327 S328 T329 S332 Y342 S367 S390 S393 S394 S401 S407 S423 S427 S448 S449 S456 S464 S467 S471 T473 T477 S633 S634 T674 S675 S676 T678 S680 S684 S723 T727 S729 T730 S742 S749 S753 S757 S758 protein RNA SCNV methylation COAD T7 S8 S193 S220 T221 S227 T229 S231 S241 S316 S326 S327 S328 T329 S332 Y342 S367 S390 S393 S394 S401 S407 S423 S427 S448 S449 S456 S464 S467 S471 T473 T477 S633 S634 T674 S675 S676 T678 S680 S684 S723 T727 S729 T730 S742 S749 S753 S757 S758 protein RNA SCNV methylation GBM T7 S8 S193 S220 T221 S227 T229 S231 S241 S316 S326 S327 S328 T329 S332 Y342 S367 S390 S393 S394 S401 S407 S423 S427 S448 S449 S456 S464 S467 S471 T473 T477 S633 S634 T674 S675 S676 T678 S680 S684 S723 T727 S729 T730 S742 S749 S753 S757 S758 protein RNA SCNV methylation HNSCC T7 S8 S193 S220 T221 S227 T229 S231 S241 S316 S326 S327 S328 T329 S332 Y342 S367 S390 S393 S394 S401 S407 S423 S427 S448 S449 S456 S464 S467 S471 T473 T477 S633 S634 T674 S675 S676 T678 S680 S684 S723 T727 S729 T730 S742 S749 S753 S757 S758 protein RNA SCNV methylation LSCC T7 S8 S193 S220 T221 S227 T229 S231 S241 S316 S326 S327 S328 T329 S332 Y342 S367 S390 S393 S394 S401 S407 S423 S427 S448 S449 S456 S464 S467 S471 T473 T477 S633 S634 T674 S675 S676 T678 S680 S684 S723 T727 S729 T730 S742 S749 S753 S757 S758 protein RNA SCNV methylation LUAD T7 S8 S193 S220 T221 S227 T229 S231 S241 S316 S326 S327 S328 T329 S332 Y342 S367 S390 S393 S394 S401 S407 S423 S427 S448 S449 S456 S464 S467 S471 T473 T477 S633 S634 T674 S675 S676 T678 S680 S684 S723 T727 S729 T730 S742 S749 S753 S757 S758 protein RNA SCNV methylation OV T7 S8 S193 S220 T221 S227 T229 S231 S241 S316 S326 S327 S328 T329 S332 Y342 S367 S390 S393 S394 S401 S407 S423 S427 S448 S449 S456 S464 S467 S471 T473 T477 S633 S634 T674 S675 S676 T678 S680 S684 S723 T727 S729 T730 S742 S749 S753 S757 S758 protein RNA SCNV methylation PDAC T7 S8 S193 S220 T221 S227 T229 S231 S241 S316 S326 S327 S328 T329 S332 Y342 S367 S390 S393 S394 S401 S407 S423 S427 S448 S449 S456 S464 S467 S471 T473 T477 S633 S634 T674 S675 S676 T678 S680 S684 S723 T727 S729 T730 S742 S749 S753 S757 S758 protein RNA SCNV methylation UCEC T7 S8 S193 S220 T221 S227 T229 S231 S241 S316 S326 S327 S328 T329 S332 Y342 S367 S390 S393 S394 S401 S407 S423 S427 S448 S449 S456 S464 S467 S471 T473 T477 S633 S634 T674 S675 S676 T678 S680 S684 S723 T727 S729 T730 S742 S749 S753 S757 S758 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T7
S8
S193
S220
T221
S227
T229
S231
S241
S316
S326
S327
S328
T329
S332
Y342
S367
S390
S393
S394
S401
S407
S423
S427
S448
S449
S456
S464
S467
S471
T473
T477
S633
S634
T674
S675
S676
T678
S680
S684
S723
T727
S729
T730
S742
S749
S753
S757
S758
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T7
S8
S193
S220
T221
S227
T229
S231
S241
S316
S326
S327
S328
T329
S332
Y342
S367
S390
S393
S394
S401
S407
S423
S427
S448
S449
S456
S464
S467
S471
T473
T477
S633
S634
T674
S675
S676
T678
S680
S684
S723
T727
S729
T730
S742
S749
S753
S757
S758
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.