Protein: ENSP00000314004
Gene: ANAPC2

LinkedOmicsKB © 2022-2023 Zhang Lab

ANAPC2:
anaphase promoting complex subunit 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S218RYYRLLQSPLCAGCS9699107-1616--19-864799912419321023118415
S314DGPARPASPEAGNTL101254106-7249523899-1035898919385831971299018
T320ASPEAGNTLRRWRCH18--44----------------
T466TDPASLETGQDSEDD5161--43261918---------30142918
S470SLETGQDSEDDSGEP1079815-5030847872-86471010272331685369018
S474GQDSEDDSGEPEDWV814316-23151089-6444----25136-
S498KSSSKRRSSDIISLL368--87--19-----1816------
S499SSSKRRSSDIISLLV257--2424--9-------------
S534LLHQFSFSPEREIRN1085937-44747094-633763576760411066326713
S732DNMVLIDSDDESDSG334--------116------3212-
Showing 1 to 10 of 12 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S218RYYRLLQSPLCAGCS1.7e-18----5e-82.3e-302.8e-6-5.5e-3-0.611.4e-3
S314DGPARPASPEAGNTL2.5e-31--2.0e-41.3e-3-7.4e-64.9e-182e-170.0621.3e-52.6e-8
T320ASPEAGNTLRRWRCH-----------
T466TDPASLETGQDSEDD-0.23--0.39------0.08-0.24
S470SLETGQDSEDDSGEP-0.36--6.8e-31.6e-4--1.2e-4-2.8e-5--6.2e-4-0.83
S474GQDSEDDSGEPEDWV-3.4e-5--0.041-------1.4e-4-
S498KSSSKRRSSDIISLL-----------
S499SSSKRRSSDIISLLV-9e-9--8.9e-9--------
S534LLHQFSFSPEREIRN6.9e-4---0.18-0.35.8e-42.1e-9-0.67-0.014.3e-3
S732DNMVLIDSDDESDSG-----------
Showing 1 to 10 of 12 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS218S314T320T466S470S474S498S499S534S732S736S738proteinRNASCNVmethylationCCRCCS218S314T320T466S470S474S498S499S534S732S736S738proteinRNASCNVmethylationCOADS218S314T320T466S470S474S498S499S534S732S736S738proteinRNASCNVmethylationGBMS218S314T320T466S470S474S498S499S534S732S736S738proteinRNASCNVmethylationHNSCCS218S314T320T466S470S474S498S499S534S732S736S738proteinRNASCNVmethylationLSCCS218S314T320T466S470S474S498S499S534S732S736S738proteinRNASCNVmethylationLUADS218S314T320T466S470S474S498S499S534S732S736S738proteinRNASCNVmethylationOVS218S314T320T466S470S474S498S499S534S732S736S738proteinRNASCNVmethylationPDACS218S314T320T466S470S474S498S499S534S732S736S738proteinRNASCNVmethylationUCECS218S314T320T466S470S474S498S499S534S732S736S738proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.