Protein: ENSP00000316029
Gene: TLN1

LinkedOmicsKB © 2022-2023 Zhang Lab

TLN1:
talin 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T23TMQFEPSTMVYDACR18------8-------------
Y26FEPSTMVYDACRIIR950222-77212427-181155518477--327518
S45EAPAGPPSDFGLFLS855930-91682529--6363574845--4820233
Y70EAGKALDYYMLRNGD101033104-7552141390-2314103949789831947178118
T78YMLRNGDTMEYRKKQ957935-4533191718---10899221966154015244
Y127GITNHDEYSLVRELM363------45---5544------
T142EEKKEEITGTLRKDK19------------54------
T144KKEEITGTLRKDKTL1090496-52429710046-30177973524841106931183
T150GTLRKDKTLLRDEKK884956-7352547163---63606761--10042789
T167KLKQKLHTDDELNWL2257-----18-------------
Showing 1 to 10 of 135 rows
102550100
rows per page

Tumor and normal comparison

Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T23TMQFEPSTMVYDACR-----------
Y26FEPSTMVYDACRIIR-8.8e-12---0.41---1.5e-8-3.9e-9---0.2
S45EAPAGPPSDFGLFLS-4.4e-19-0.97-5.4e-9---3.2e-19-1.7e-22-5.2e-6-
Y70EAGKALDYYMLRNGD-1.2e-5-0.057---6.9e-3-1.2e-18-1.3e-90.869.5e-9-0.069
T78YMLRNGDTMEYRKKQ-1.9e-6-3.2e-3----3.3e-27-3.0e-5-0.154.5e-3-
Y127GITNHDEYSLVRELM-----------
T142EEKKEEITGTLRKDK-----------
T144KKEEITGTLRKDKTL-3.7e-31-0.54-7.7e-20--9.1e-5-4.9e-19-1.1e-12-1.5e-30.36-
T150GTLRKDKTLLRDEKK-7.4e-18--3.9e-4-5.4e-12---1.5e-12-6.4e-4-0.092-
T167KLKQKLHTDDELNWL-----------
Showing 1 to 10 of 135 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

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

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

Loading, please wait
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.