PPP2R5C: protein phosphatase 2 regulatory subunit B'gamma
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2iae chain B
2iae chain E
2jak chain A
2npp chain B
2npp chain E
2nyl chain B
2nyl chain E
2nym chain B
2nym chain E
3fga chain B
5jja chain A
5jja chain B
5k6s chain A
5sw9 chain A
5swf chain A
6oyl chain A
6toq chain AAA
6voy chain E
6voy chain F
6vro chain A
7ouf chain C
7ouf chain F
7oug chain C
7oug chain F
7ouh chain C
7ouh chain F
7pel chain C
7pel chain F
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S497 RPLARRKS ELPQDPH 7 1124 - - 103 80 - - 99 - 108 62 108 99 106 97 - - 105 44 95 18 S520 CRADELAS QDGR___ 2 46 - - - - - - - - - - 20 18 4 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S497 RPLARRKS ELPQDPH -4.5e-4 - 1.5e-12 - - -0.017 -8.4e-23 -5.2e-8 - 2.2e-3 -0.29 S520 CRADELAS QDGR___ 6.9e-7 - - - - - 6.9e-7 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S497
S520
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S497 S520 protein RNA SCNV methylation CCRCC S497 S520 protein RNA SCNV methylation COAD S497 S520 protein RNA SCNV methylation GBM S497 S520 protein RNA SCNV methylation HNSCC S497 S520 protein RNA SCNV methylation LSCC S497 S520 protein RNA SCNV methylation LUAD S497 S520 protein RNA SCNV methylation OV S497 S520 protein RNA SCNV methylation PDAC S497 S520 protein RNA SCNV methylation UCEC S497 S520 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S497
S520
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S497
S520
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.