Protein: ENSP00000389168
Gene: PPP1R12A

LinkedOmicsKB © 2022-2023 Zhang Lab

PPP1R12A:
protein phosphatase 1 regulatory subunit 12A

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S20QLKRWIGSETDLEPP4160----131490-----45----1816
T22KRWIGSETDLEPPVV139--2019----------------
S292KKQNLLHSEKRDKKS9100290-8268--27-102596458106967197408916
S299SEKRDKKSPLIESTA101327114-9472686699-81471089911010115297419518
S304KKSPLIESTANMDNN188-------------------
T305KSPLIESTANMDNNQ31139-544136--------------
S336KNASRIESLEQEKVD7540--6241--63-412239362925--73336016
S354EGKKDESSCSSEEDE341----------531311-----9
S356KKDESSCSSEEDEED5165------15---25152318--414816
S357KDESSCSSEEDEEDD712513-88--9---5553--414816
Showing 1 to 10 of 84 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S20QLKRWIGSETDLEPP-----------
T22KRWIGSETDLEPPVV3.5e-3-3.5e-3--------
S292KKQNLLHSEKRDKKS0.28--0.04--2.4e-50.30.055--7.6e-50.15
S299SEKRDKKSPLIESTA-2.1e-13--0.044-3.4e-3-1.6e-4-1.3e-14-9e-27-0.016-0.025
S304KKSPLIESTANMDNN-----------
T305KSPLIESTANMDNNQ-0.38--0.38--------
S336KNASRIESLEQEKVD0.74-8e-8--0.24-5.1e-4-0.64-0.83-2.9e-4
S354EGKKDESSCSSEEDE-----------
S356KKDESSCSSEEDEED2.4e-13-----1.5e-53.9e-3--4.3e-8
S357KDESSCSSEEDEEDD2.9e-8---------2.9e-8
Showing 1 to 10 of 84 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS20T22S292S299S304T305S336S354S356S357S365S367S386S387T388T396T397T399S402T406T408S409T419S422S432T443S445Y446T453S472S473S477S478S479S507T508S509S519T524S525S526S527S541S542S547S554T590S591S601S602S607S608T609S610S618T619S668T671S680S695T696S746T786S802S852T853S856T859S862S871T873S877S886S888S894S896Y901S903S908S910Y913S929S978S995proteinRNASCNVmethylationCCRCCS20T22S292S299S304T305S336S354S356S357S365S367S386S387T388T396T397T399S402T406T408S409T419S422S432T443S445Y446T453S472S473S477S478S479S507T508S509S519T524S525S526S527S541S542S547S554T590S591S601S602S607S608T609S610S618T619S668T671S680S695T696S746T786S802S852T853S856T859S862S871T873S877S886S888S894S896Y901S903S908S910Y913S929S978S995proteinRNASCNVmethylationCOADS20T22S292S299S304T305S336S354S356S357S365S367S386S387T388T396T397T399S402T406T408S409T419S422S432T443S445Y446T453S472S473S477S478S479S507T508S509S519T524S525S526S527S541S542S547S554T590S591S601S602S607S608T609S610S618T619S668T671S680S695T696S746T786S802S852T853S856T859S862S871T873S877S886S888S894S896Y901S903S908S910Y913S929S978S995proteinRNASCNVmethylationGBMS20T22S292S299S304T305S336S354S356S357S365S367S386S387T388T396T397T399S402T406T408S409T419S422S432T443S445Y446T453S472S473S477S478S479S507T508S509S519T524S525S526S527S541S542S547S554T590S591S601S602S607S608T609S610S618T619S668T671S680S695T696S746T786S802S852T853S856T859S862S871T873S877S886S888S894S896Y901S903S908S910Y913S929S978S995proteinRNASCNVmethylationHNSCCS20T22S292S299S304T305S336S354S356S357S365S367S386S387T388T396T397T399S402T406T408S409T419S422S432T443S445Y446T453S472S473S477S478S479S507T508S509S519T524S525S526S527S541S542S547S554T590S591S601S602S607S608T609S610S618T619S668T671S680S695T696S746T786S802S852T853S856T859S862S871T873S877S886S888S894S896Y901S903S908S910Y913S929S978S995proteinRNASCNVmethylationLSCCS20T22S292S299S304T305S336S354S356S357S365S367S386S387T388T396T397T399S402T406T408S409T419S422S432T443S445Y446T453S472S473S477S478S479S507T508S509S519T524S525S526S527S541S542S547S554T590S591S601S602S607S608T609S610S618T619S668T671S680S695T696S746T786S802S852T853S856T859S862S871T873S877S886S888S894S896Y901S903S908S910Y913S929S978S995proteinRNASCNVmethylationLUADS20T22S292S299S304T305S336S354S356S357S365S367S386S387T388T396T397T399S402T406T408S409T419S422S432T443S445Y446T453S472S473S477S478S479S507T508S509S519T524S525S526S527S541S542S547S554T590S591S601S602S607S608T609S610S618T619S668T671S680S695T696S746T786S802S852T853S856T859S862S871T873S877S886S888S894S896Y901S903S908S910Y913S929S978S995proteinRNASCNVmethylationOVS20T22S292S299S304T305S336S354S356S357S365S367S386S387T388T396T397T399S402T406T408S409T419S422S432T443S445Y446T453S472S473S477S478S479S507T508S509S519T524S525S526S527S541S542S547S554T590S591S601S602S607S608T609S610S618T619S668T671S680S695T696S746T786S802S852T853S856T859S862S871T873S877S886S888S894S896Y901S903S908S910Y913S929S978S995proteinRNASCNVmethylationPDACS20T22S292S299S304T305S336S354S356S357S365S367S386S387T388T396T397T399S402T406T408S409T419S422S432T443S445Y446T453S472S473S477S478S479S507T508S509S519T524S525S526S527S541S542S547S554T590S591S601S602S607S608T609S610S618T619S668T671S680S695T696S746T786S802S852T853S856T859S862S871T873S877S886S888S894S896Y901S903S908S910Y913S929S978S995proteinRNASCNVmethylationUCECS20T22S292S299S304T305S336S354S356S357S365S367S386S387T388T396T397T399S402T406T408S409T419S422S432T443S445Y446T453S472S473S477S478S479S507T508S509S519T524S525S526S527S541S542S547S554T590S591S601S602S607S608T609S610S618T619S668T671S680S695T696S746T786S802S852T853S856T859S862S871T873S877S886S888S894S896Y901S903S908S910Y913S929S978S995proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.