HTR2A: 5-hydroxytryptamine receptor 2A
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
6a93 chain A
6a93 chain B
6a94 chain A
6a94 chain B
6wgt chain A
6wgt chain B
6wgt chain C
6wh4 chain A
6wh4 chain B
6wh4 chain C
6wha chain A
7ran chain A
7vod chain A
7voe chain A
7wc4 chain A
7wc5 chain A
7wc6 chain A
7wc7 chain A
7wc8 chain A
7wc9 chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S298 SEKLFQRS IHREPGS 1 91 - - - - - - 91 - - - - - - - - - - - - - S461 EEASKDNS DGVNEKV 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S298 SEKLFQRS IHREPGS - - - - - - - - - - - S461 EEASKDNS DGVNEKV - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S298
S461
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S298 S461 protein RNA SCNV methylation CCRCC S298 S461 protein RNA SCNV methylation COAD S298 S461 protein RNA SCNV methylation GBM S298 S461 protein RNA SCNV methylation HNSCC S298 S461 protein RNA SCNV methylation LSCC S298 S461 protein RNA SCNV methylation LUAD S298 S461 protein RNA SCNV methylation OV S298 S461 protein RNA SCNV methylation PDAC S298 S461 protein RNA SCNV methylation UCEC S298 S461 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S298
S461
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S298
S461
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.