- HTR2A:
- 5-hydroxytryptamine receptor 2A
Lollipop plot
Phosphosites location and occurrence
Structure
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Site
| Sequence | Cohorts | Total | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N |
S298 | SEKLFQRSIHREPGS | 1 | 91 | - | - | - | - | - | - | 91 | - | - | - | - | - | - | - | - | - | - | - | - | - |
S461 | EEASKDNSDGVNEKV | 1 | 9 | - | - | - | - | - | - | 9 | - | - | - | - | - | - | - | - | - | - | - | - | - |
Tumor and normal comparison
Site
| Sequence | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S298 | SEKLFQRSIHREPGS | - | - | - | - | - | - | - | - | - | - | - |
S461 | EEASKDNSDGVNEKV | - | - | - | - | - | - | - | - | - | - | - |
Phenotype and mutation association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
HALLMARK_KRAS_SIGNALING_DN | S298 | 7.7e-8 | - | - | - | 7.7e-8 | - | - | - | - | - | - |
HALLMARK_SPERMATOGENESIS | S298 | 1.6e-5 | - | - | - | 1.6e-5 | - | - | - | - | - | - |
HALLMARK_PANCREAS_BETA_CELLS | S298 | 4.2e-5 | - | - | - | 4.2e-5 | - | - | - | - | - | - |
KINASE-PSP_CDK5 | S298 | 7.9e-4 | - | - | - | 7.9e-4 | - | - | - | - | - | - |
DISEASE-PSP_Alzheimer's_disease | S298 | 1.9e-3 | - | - | - | 1.9e-3 | - | - | - | - | - | - |
HALLMARK_HEDGEHOG_SIGNALING | S298 | 0.003 | - | - | - | 0.003 | - | - | - | - | - | - |
xcell: Common myeloid progenitor | S298 | 6.4e-3 | - | - | - | 6.4e-3 | - | - | - | - | - | - |
KINASE-PSP_GSK3B | S298 | 0.016 | - | - | - | 0.016 | - | - | - | - | - | - |
xcell: T cell CD4+ (non-regulatory) | S298 | 0.017 | - | - | - | 0.017 | - | - | - | - | - | - |
xcell: Hematopoietic stem cell | S298 | 0.046 | - | - | - | 0.046 | - | - | - | - | - | - |
Cis-association
Kinase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Phosphatase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
PTPN12 | S298 | -1.4e-5 | - | - | - | -1.4e-5 | - | - | - | - | - | - |
INPP5B | S298 | -4.0e-5 | - | - | - | -4.0e-5 | - | - | - | - | - | - |
MTMR14 | S298 | -8.4e-5 | - | - | - | -8.3e-5 | - | - | - | - | - | - |
PPIP5K2 | S298 | -8.9e-5 | - | - | - | -8.9e-5 | - | - | - | - | - | - |
PPM1M | S298 | -1.1e-4 | - | - | - | -1.1e-4 | - | - | - | - | - | - |
IMPA2 | S298 | -1.4e-4 | - | - | - | -1.4e-4 | - | - | - | - | - | - |
PTPN6 | S298 | -1.9e-4 | - | - | - | -1.9e-4 | - | - | - | - | - | - |
PTPN7 | S298 | -4.1e-4 | - | - | - | -4.1e-4 | - | - | - | - | - | - |
PTPN2 | S298 | -7.7e-4 | - | - | - | -7.7e-4 | - | - | - | - | - | - |
PTPN14 | S298 | -1.1e-3 | - | - | - | -1.1e-3 | - | - | - | - | - | - |