KANK2: KN motif and ankyrin repeat domains 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4hbd chain A
5ybv chain A
5ybv chain B
6tmd chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S19 PGTPGPAS PPAFPAK 6 194 - - 12 9 - - 9 - 5 3 15 14 45 41 - - - - 36 5 S71 VQRRPRLS SLPRGPG 2 86 - - - - 15 29 - - - - - - - - - - 30 12 - - S72 QRRPRLSS LPRGPGS 2 43 17 - - - 11 15 - - - - - - - - - - - - - - S79 SLPRGPGS WWTSTES 4 73 17 - - - - - - - - - 5 5 4 4 - - - - 36 2 S83 GPGSWWTS TESLCSN 10 1294 87 - 90 68 87 92 89 - 102 59 73 67 83 77 54 13 99 41 95 18 T84 PGSWWTST ESLCSNA 8 176 8 - 4 4 14 30 - - 12 7 10 9 8 8 - - 36 17 7 2 S86 SWWTSTES LCSNASG 7 282 16 - 4 4 35 37 - - - - 25 23 13 12 - - 12 5 78 18 S89 TSTESLCS NASGDSR 7 135 8 - 5 4 4 5 - - 11 7 - - 17 17 - - 6 4 42 5 S92 ESLCSNAS GDSRHSA 10 704 23 - 5 4 42 47 27 - 59 34 58 56 37 31 20 6 100 42 95 18 S95 CSNASGDS RHSAYSY 2 36 - - - - 3 6 - - - - - - - - - - - - 23 4
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S19 PGTPGPAS PPAFPAK -4.9e-21 - - - - - - -4.9e-21 - - - S71 VQRRPRLS SLPRGPG -0.077 - - - - - - - - -0.077 - S72 QRRPRLSS LPRGPGS - - - - - - - - - - - S79 SLPRGPGS WWTSTES - - - - - - - - - - - S83 GPGSWWTS TESLCSN -3.4e-38 - 1.1e-4 -6e-23 - -7e-19 -1.4e-21 -5.1e-26 -0.24 0.16 -0.071 T84 PGSWWTST ESLCSNA 0.001 - - - - - - - - 0.001 - S86 SWWTSTES LCSNASG -2.6e-7 - - -1.0e-5 - - -7.7e-9 - - - 0.2 S89 TSTESLCS NASGDSR - - - - - - - - - - - S92 ESLCSNAS GDSRHSA -4.1e-13 - - -4.7e-6 - -2e-12 -1.1e-17 -1.6e-3 - 5.1e-5 0.13 S95 CSNASGDS RHSAYSY - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S19
S71
S72
S79
S83
T84
S86
S89
S92
S95
S98
Y100
S101
T141
T143
S147
T149
S151
S155
T156
S158
T168
S171
S172
S175
T176
S181
S246
S266
S323
S356
S375
S406
T408
S411
S425
S426
S427
S428
S432
S436
S463
S466
T472
S481
S498
Y508
S512
S522
S540
S558
S565
S568
T573
S578
S580
T582
S843
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S19 S71 S72 S79 S83 T84 S86 S89 S92 S95 S98 Y100 S101 T141 T143 S147 T149 S151 S155 T156 S158 T168 S171 S172 S175 T176 S181 S246 S266 S323 S356 S375 S406 T408 S411 S425 S426 S427 S428 S432 S436 S463 S466 T472 S481 S498 Y508 S512 S522 S540 S558 S565 S568 T573 S578 S580 T582 S843 protein RNA SCNV methylation CCRCC S19 S71 S72 S79 S83 T84 S86 S89 S92 S95 S98 Y100 S101 T141 T143 S147 T149 S151 S155 T156 S158 T168 S171 S172 S175 T176 S181 S246 S266 S323 S356 S375 S406 T408 S411 S425 S426 S427 S428 S432 S436 S463 S466 T472 S481 S498 Y508 S512 S522 S540 S558 S565 S568 T573 S578 S580 T582 S843 protein RNA SCNV methylation COAD S19 S71 S72 S79 S83 T84 S86 S89 S92 S95 S98 Y100 S101 T141 T143 S147 T149 S151 S155 T156 S158 T168 S171 S172 S175 T176 S181 S246 S266 S323 S356 S375 S406 T408 S411 S425 S426 S427 S428 S432 S436 S463 S466 T472 S481 S498 Y508 S512 S522 S540 S558 S565 S568 T573 S578 S580 T582 S843 protein RNA SCNV methylation GBM S19 S71 S72 S79 S83 T84 S86 S89 S92 S95 S98 Y100 S101 T141 T143 S147 T149 S151 S155 T156 S158 T168 S171 S172 S175 T176 S181 S246 S266 S323 S356 S375 S406 T408 S411 S425 S426 S427 S428 S432 S436 S463 S466 T472 S481 S498 Y508 S512 S522 S540 S558 S565 S568 T573 S578 S580 T582 S843 protein RNA SCNV methylation HNSCC S19 S71 S72 S79 S83 T84 S86 S89 S92 S95 S98 Y100 S101 T141 T143 S147 T149 S151 S155 T156 S158 T168 S171 S172 S175 T176 S181 S246 S266 S323 S356 S375 S406 T408 S411 S425 S426 S427 S428 S432 S436 S463 S466 T472 S481 S498 Y508 S512 S522 S540 S558 S565 S568 T573 S578 S580 T582 S843 protein RNA SCNV methylation LSCC S19 S71 S72 S79 S83 T84 S86 S89 S92 S95 S98 Y100 S101 T141 T143 S147 T149 S151 S155 T156 S158 T168 S171 S172 S175 T176 S181 S246 S266 S323 S356 S375 S406 T408 S411 S425 S426 S427 S428 S432 S436 S463 S466 T472 S481 S498 Y508 S512 S522 S540 S558 S565 S568 T573 S578 S580 T582 S843 protein RNA SCNV methylation LUAD S19 S71 S72 S79 S83 T84 S86 S89 S92 S95 S98 Y100 S101 T141 T143 S147 T149 S151 S155 T156 S158 T168 S171 S172 S175 T176 S181 S246 S266 S323 S356 S375 S406 T408 S411 S425 S426 S427 S428 S432 S436 S463 S466 T472 S481 S498 Y508 S512 S522 S540 S558 S565 S568 T573 S578 S580 T582 S843 protein RNA SCNV methylation OV S19 S71 S72 S79 S83 T84 S86 S89 S92 S95 S98 Y100 S101 T141 T143 S147 T149 S151 S155 T156 S158 T168 S171 S172 S175 T176 S181 S246 S266 S323 S356 S375 S406 T408 S411 S425 S426 S427 S428 S432 S436 S463 S466 T472 S481 S498 Y508 S512 S522 S540 S558 S565 S568 T573 S578 S580 T582 S843 protein RNA SCNV methylation PDAC S19 S71 S72 S79 S83 T84 S86 S89 S92 S95 S98 Y100 S101 T141 T143 S147 T149 S151 S155 T156 S158 T168 S171 S172 S175 T176 S181 S246 S266 S323 S356 S375 S406 T408 S411 S425 S426 S427 S428 S432 S436 S463 S466 T472 S481 S498 Y508 S512 S522 S540 S558 S565 S568 T573 S578 S580 T582 S843 protein RNA SCNV methylation UCEC S19 S71 S72 S79 S83 T84 S86 S89 S92 S95 S98 Y100 S101 T141 T143 S147 T149 S151 S155 T156 S158 T168 S171 S172 S175 T176 S181 S246 S266 S323 S356 S375 S406 T408 S411 S425 S426 S427 S428 S432 S436 S463 S466 T472 S481 S498 Y508 S512 S522 S540 S558 S565 S568 T573 S578 S580 T582 S843 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S19
S71
S72
S79
S83
T84
S86
S89
S92
S95
S98
Y100
S101
T141
T143
S147
T149
S151
S155
T156
S158
T168
S171
S172
S175
T176
S181
S246
S266
S323
S356
S375
S406
T408
S411
S425
S426
S427
S428
S432
S436
S463
S466
T472
S481
S498
Y508
S512
S522
S540
S558
S565
S568
T573
S578
S580
T582
S843
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S19
S71
S72
S79
S83
T84
S86
S89
S92
S95
S98
Y100
S101
T141
T143
S147
T149
S151
S155
T156
S158
T168
S171
S172
S175
T176
S181
S246
S266
S323
S356
S375
S406
T408
S411
S425
S426
S427
S428
S432
S436
S463
S466
T472
S481
S498
Y508
S512
S522
S540
S558
S565
S568
T573
S578
S580
T582
S843
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.