BCL11A: BAF chromatin remodeling complex subunit BCL11A
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5vtb chain B
6ki6 chain A
6ki6 chain B
6u9q chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S74 KRKQCNGS LCLEKAV 7 364 - - 12 12 - - 9 - 85 49 73 66 5 4 - - 8 4 30 7 S86 KAVDKPPS PSPIEMK 8 866 - - 54 42 83 87 73 - 108 62 39 35 17 17 - - 104 44 83 18 S88 VDKPPSPS PIEMKKA 3 69 - - 8 8 - - - - - - 18 16 - - - - - - 17 2 T106 VEVGIQVT PEDDDCL 2 29 - - - - - - - - 6 3 10 10 - - - - - - - - S114 PEDDDCLS TSSRGIC 3 37 - - - - - - - - 6 3 5 4 - - - - - - 17 2 S116 DDDCLSTS SRGICPK 3 33 - - - - - - - - 12 8 5 4 - - - - - - 4 - S201 GLRIYLES EHGSPLT 1 10 - - - - - - - - - - 5 5 - - - - - - - - S205 YLESEHGS PLTPRVG 8 807 - - 20 20 48 42 90 - 103 59 103 93 68 59 - - 31 11 51 9 T208 SEHGSPLT PRVGIPS 7 290 - - - - 29 33 18 - 5 3 93 81 8 7 - - 5 2 6 - T326 LRELAGNT SSPPLSP 6 237 - - - - - - 10 - 24 13 64 59 5 4 - - 29 10 17 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S74 KRKQCNGS LCLEKAV 5.2e-7 - - - - -0.025 9.6e-21 - - - - S86 KAVDKPPS PSPIEMK 1.2e-5 - 7.8e-3 2.5e-8 - -3e-7 3e-13 - - -3.1e-5 7.9e-6 S88 VDKPPSPS PIEMKKA - - - - - - - - - - - T106 VEVGIQVT PEDDDCL - - - - - - - - - - - S114 PEDDDCLS TSSRGIC - - - - - - - - - - - S116 DDDCLSTS SRGICPK - - - - - - - - - - - S201 GLRIYLES EHGSPLT - - - - - - - - - - - S205 YLESEHGS PLTPRVG 1.3e-7 - -0.99 4.6e-3 - 0.04 1.3e-19 0.045 - -2.6e-3 - T208 SEHGSPLT PRVGIPS 5.5e-13 - - 0.2 - - 4.7e-19 - - - - T326 LRELAGNT SSPPLSP 4.4e-4 - - - - 0.89 1.8e-10 - - -0.67 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S74
S86
S88
T106
S114
S116
S201
S205
T208
T326
S327
S328
S332
S337
T357
S432
S438
T444
S446
S447
T452
S453
T584
S589
S594
S608
S612
S625
S627
S628
S630
S679
T701
S718
S721
T722
S734
S735
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S74 S86 S88 T106 S114 S116 S201 S205 T208 T326 S327 S328 S332 S337 T357 S432 S438 T444 S446 S447 T452 S453 T584 S589 S594 S608 S612 S625 S627 S628 S630 S679 T701 S718 S721 T722 S734 S735 protein RNA SCNV methylation CCRCC S74 S86 S88 T106 S114 S116 S201 S205 T208 T326 S327 S328 S332 S337 T357 S432 S438 T444 S446 S447 T452 S453 T584 S589 S594 S608 S612 S625 S627 S628 S630 S679 T701 S718 S721 T722 S734 S735 protein RNA SCNV methylation COAD S74 S86 S88 T106 S114 S116 S201 S205 T208 T326 S327 S328 S332 S337 T357 S432 S438 T444 S446 S447 T452 S453 T584 S589 S594 S608 S612 S625 S627 S628 S630 S679 T701 S718 S721 T722 S734 S735 protein RNA SCNV methylation GBM S74 S86 S88 T106 S114 S116 S201 S205 T208 T326 S327 S328 S332 S337 T357 S432 S438 T444 S446 S447 T452 S453 T584 S589 S594 S608 S612 S625 S627 S628 S630 S679 T701 S718 S721 T722 S734 S735 protein RNA SCNV methylation HNSCC S74 S86 S88 T106 S114 S116 S201 S205 T208 T326 S327 S328 S332 S337 T357 S432 S438 T444 S446 S447 T452 S453 T584 S589 S594 S608 S612 S625 S627 S628 S630 S679 T701 S718 S721 T722 S734 S735 protein RNA SCNV methylation LSCC S74 S86 S88 T106 S114 S116 S201 S205 T208 T326 S327 S328 S332 S337 T357 S432 S438 T444 S446 S447 T452 S453 T584 S589 S594 S608 S612 S625 S627 S628 S630 S679 T701 S718 S721 T722 S734 S735 protein RNA SCNV methylation LUAD S74 S86 S88 T106 S114 S116 S201 S205 T208 T326 S327 S328 S332 S337 T357 S432 S438 T444 S446 S447 T452 S453 T584 S589 S594 S608 S612 S625 S627 S628 S630 S679 T701 S718 S721 T722 S734 S735 protein RNA SCNV methylation OV S74 S86 S88 T106 S114 S116 S201 S205 T208 T326 S327 S328 S332 S337 T357 S432 S438 T444 S446 S447 T452 S453 T584 S589 S594 S608 S612 S625 S627 S628 S630 S679 T701 S718 S721 T722 S734 S735 protein RNA SCNV methylation PDAC S74 S86 S88 T106 S114 S116 S201 S205 T208 T326 S327 S328 S332 S337 T357 S432 S438 T444 S446 S447 T452 S453 T584 S589 S594 S608 S612 S625 S627 S628 S630 S679 T701 S718 S721 T722 S734 S735 protein RNA SCNV methylation UCEC S74 S86 S88 T106 S114 S116 S201 S205 T208 T326 S327 S328 S332 S337 T357 S432 S438 T444 S446 S447 T452 S453 T584 S589 S594 S608 S612 S625 S627 S628 S630 S679 T701 S718 S721 T722 S734 S735 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S74
S86
S88
T106
S114
S116
S201
S205
T208
T326
S327
S328
S332
S337
T357
S432
S438
T444
S446
S447
T452
S453
T584
S589
S594
S608
S612
S625
S627
S628
S630
S679
T701
S718
S721
T722
S734
S735
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S74
S86
S88
T106
S114
S116
S201
S205
T208
T326
S327
S328
S332
S337
T357
S432
S438
T444
S446
S447
T452
S453
T584
S589
S594
S608
S612
S625
S627
S628
S630
S679
T701
S718
S721
T722
S734
S735
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.