Basic information
- Phenotype
- cibersort: Neutrophil
- Description
- Estimated fraction of neutrophils in the tumor compared to 21 other immune cells defined by CIBERSORT based on RNA expression data.
- Source
- https://www.nature.com/articles/nmeth.3337
- Method
- The R package immunedeconv (V2.0.4) (PMID: 31510660) was used to perform immune cell deconvolution using RNA expression data (TPM). CIBERSORT (PMID: 25822800) was performed in the ‘abs’ mode.
- Genes
-
- AIF1
- AIM2
- ALOX5
- APOBEC3A
- AQP9
- BCL2A1
- BRAF
- BST1
- BTNL8
- C3AR1
- C5AR1
- CAMP
- CCL4
- CCR3
- CD300A
- CD37
- CD3E
- CDA
- CEACAM3
- CFP
- CHI3L1
- CHST15
- CHST7
- CLC
- CLEC4A
- CLEC7A
- CREB5
- CSF3R
- CST7
- CXCR1
- CXCR2
- DPEP2
- FCGR2B
- FCGR3B
- FCN1
- FFAR2
- FPR1
- FPR2
- GPR65
- HAL
- HCK
- HHEX
- HK3
- HPSE
- HSPA6
- Array
- IGSF6
- IL18RAP
- IL1B
- IL2RB
- IL4R
- IL7R
- LILRA2
- LILRB2
- LRMP
- LST1
- LTB
- LY86
- MAK
- MEFV
- MGAM
- MMP25
- MMP9
- MNDA
- MS4A6A
- MXD1
- NCF2
- NFE2
- NOD2
- NPIPB15
- NPL
- P2RX1
- P2RY13
- P2RY14
- PADI4
- PBXIP1
- PGLYRP1
- PLEKHG3
- QPCT
- RASGRP2
- REPS2
- RNASE2
- RNASE6
- RSAD2
- S100A12
- SAMSN1
- SELL
- SLC15A3
- STEAP4
- TLR2
- TLR8
- TNFAIP6
- TNFRSF10C
- TPSAB1
- TREM1
- TREML2
- VNN1
- VNN2
- VNN3
- More...
Gene association
Number of significant genes with P-value ≤ 10-6 for each cohorts are summarized in bar plots. The scatter plot highlights significant associations diven by protein rather than mRNA abundance.
Association of protein abundance of genes
| Signed p-values | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with cibersort: Neutrophil to WebGestalt.
Phosphosite association
Number of significant genes with P-value ≤ 10-6 for each cohorts are summarized in the bar plot. The scatter plot highlights significant associations diven by phosphorylation rather than protein abundance.
| Signed p-values | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | Protein | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
Gene set enrichment analysis
Submit phosphorylation sites and the common logarithm of the p-values of their association with cibersort: Neutrophil to WebGestalt.