Basic information
- Phenotype
- cibersort: Monocyte
- Description
- Estimated fraction of monocytes in the tumor compared to 21 other immune cells defined by CIBERSORT based on RNA expression data.
- Source
- https://www.nature.com/articles/nmeth.3337
- Method
- The R package immunedeconv (V2.0.4) (PMID: 31510660) was used to perform immune cell deconvolution using RNA expression data (TPM). CIBERSORT (PMID: 25822800) was performed in the ‘abs’ mode.
- Genes
-
- ADRB2
- AIF1
- AIM2
- ALOX5
- APOBEC3A
- APOBEC3G
- APOL3
- AQP9
- ASGR1
- ASGR2
- BCL2A1
- BST1
- C3AR1
- C5AR1
- CCL4
- CCR2
- CCR5
- CD180
- CD1C
- CD1D
- CD244
- CD300A
- CD33
- CD37
- CD4
- CD68
- CD86
- CDA
- CFP
- CHST15
- CLEC10A
- CLEC4A
- CLEC7A
- CSF3R
- CXCL10
- CYP27A1
- DPEP2
- EAF2
- EGR2
- FCER1A
- FCN1
- FES
- FLVCR2
- FOSB
- FPR1
- FPR2
- FZD2
- GPR65
- HAL
- HCK
- HHEX
- HK3
- HNMT
- HPSE
- HSPA6
- IGSF6
- IL1B
- IL4R
- IRF8
- KYNU
- LILRA2
- LILRB2
- LRMP
- LST1
- LY86
- MEFV
- MNDA
- MS4A6A
- NCF2
- NFE2
- NLRP3
- NOD2
- NPL
- P2RX1
- P2RY13
- PADI4
- PIK3IP1
- PLA2G7
- PTGER2
- PTGIR
- QPCT
- RASGRP2
- RASSF4
- RNASE2
- RNASE6
- S100A12
- SAMSN1
- SELL
- SIK1
- SLC15A3
- SLC2A6
- TLR2
- TLR7
- TLR8
- TPSAB1
- TREM1
- VNN1
- VNN2
- ZFP36L2
- More...
Gene association
Number of significant genes with P-value ≤ 10-6 for each cohorts are summarized in bar plots. The scatter plot highlights significant associations diven by protein rather than mRNA abundance.
Association of protein abundance of genes
| Signed p-values | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with cibersort: Monocyte to WebGestalt.
Phosphosite association
Number of significant genes with P-value ≤ 10-6 for each cohorts are summarized in the bar plot. The scatter plot highlights significant associations diven by phosphorylation rather than protein abundance.
| Signed p-values | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | Protein | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
Gene set enrichment analysis
Submit phosphorylation sites and the common logarithm of the p-values of their association with cibersort: Monocyte to WebGestalt.