DNAJA3:
DnaJ heat shock protein family (Hsp40) member A3

Lollipop plot

Phosphosites location and occurrence

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Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S44AWLSRKLSVPAFASS110--------64----------
Y113QKEIKKAYYQLAKKY354--44--------88----30-
Y114KEIKKAYYQLAKKYH354--44--------88----30-
Y399GIPRINSYGYGDHYI139--2019----------------
Showing 1 to 4 of 4 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S44AWLSRKLSVPAFASS-----------
Y113QKEIKKAYYQLAKKY-----------
Y114KEIKKAYYQLAKKYH-----------
Y399GIPRINSYGYGDHYI0.28-0.28--------
Showing 1 to 4 of 4 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
PIK3CA mutationY1140.006---------0.006
PIK3CA mutationY1130.006---------0.006
Clinical: Path_Stage_pTY1140.014---------0.014
Clinical: Path_Stage_pTY1130.014---------0.014
xcell: Endothelial cellY1130.018---------0.018
xcell: Endothelial cellY1140.018---------0.018
PROGENy: EstrogenY1140.021---------0.021
PROGENy: EstrogenY1130.021---------0.021
Clinical: StageY1140.025---------0.025
Clinical: StageY1130.025---------0.025
Showing 1 to 10 of 1032 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS44Y113Y114Y399proteinRNASCNVmethylationCCRCCS44Y113Y114Y399proteinRNASCNVmethylationCOADS44Y113Y114Y399proteinRNASCNVmethylationGBMS44Y113Y114Y399proteinRNASCNVmethylationHNSCCS44Y113Y114Y399proteinRNASCNVmethylationLSCCS44Y113Y114Y399proteinRNASCNVmethylationLUADS44Y113Y114Y399proteinRNASCNVmethylationOVS44Y113Y114Y399proteinRNASCNVmethylationPDACS44Y113Y114Y399proteinRNASCNVmethylationUCECS44Y113Y114Y399proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
MTMR14Y399-3.3e-3--3.3e-3--------
PPIP5K2Y114-0.008----------0.008
PPIP5K2Y113-0.008----------0.008
PTPRCY399-0.008--0.008--------
PTPN6Y399-0.011--0.011--------
ACP2Y399-0.015--0.015--------
GAKY399-0.019--0.019--------
PTPN6Y114-0.024----------0.024
PTPN6Y113-0.024----------0.024
PTPRFY113-0.028----------0.028
Showing 1 to 10 of 960 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.