Basic information
- Phenotype
- cibersort: B cell naive
- Description
- Estimated fraction of naïve B cells in the tumor compared to 21 other immune cells defined by CIBERSORT based on RNA expression data.
- Source
- https://www.nature.com/articles/nmeth.3337
- Method
- The R package immunedeconv (V2.0.4) (PMID: 31510660) was used to perform immune cell deconvolution using RNA expression data (TPM). CIBERSORT (PMID: 25822800) was performed in the ‘abs’ mode.
- Genes
-
- ADAM28
- BACH2
- BANK1
- BEND5
- Array
- Array
- ACP5
- ALOX5
- APOBEC3G
- BCL7A
- BIRC3
- BLK
- BRAF
- C11orf80
- CCL4
- CCR7
- CD180
- CD19
- CD1A
- CD1B
- CD1C
- CD22
- CD37
- CD38
- CD3E
- CD40
- CD69
- CD72
- CD79A
- Array
- CD79B
- CD8A
- CHI3L2
- Array
- CLEC2D
- CPA3
- CR2
- CXCL10
- CXCL9
- CYP27B1
- DPEP2
- EAF2
- ETS1
- FCER2
- FCGR2B
- FCRL2
- GNG7
- GPR18
- HHEX
- HLA-DOB
- HLA-DQA1
- IGHD
- IL1B
- IL2RB
- IL4R
- IRF8
- KLRG1
- KLRK1
- LRMP
- LTB
- LY86
- MEP1A
- MMP12
- MS4A1
- MS4A6A
- NIPSNAP3B
- NPIPB15
- P2RX5
- P2RY14
- PASK
- PIK3IP1
- PNOC
- PSG2
- PTPRCAP
- Array
- PVRIG
- RALGPS2
- RASGRP2
- RNASE6
- Array
- SELL
- SIK1
- SIT1
- SKAP1
- SLAMF1
- SP140
- SPIB
- SPOCK2
- STAP1
- TCL1A
- TMEM156
- TPSAB1
- TRIB2
- UGT1A8
- Array
- VPREB3
- ZFP36L2
- ZNF286A
- Array
- More...
Gene association
Number of significant genes with P-value ≤ 10-6 for each cohorts are summarized in bar plots. The scatter plot highlights significant associations diven by protein rather than mRNA abundance.
Association of protein abundance of genes
| Signed p-values | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with cibersort: B cell naive to WebGestalt.
Phosphosite association
Number of significant genes with P-value ≤ 10-6 for each cohorts are summarized in the bar plot. The scatter plot highlights significant associations diven by phosphorylation rather than protein abundance.
| Signed p-values | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | Protein | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
Gene set enrichment analysis
Submit phosphorylation sites and the common logarithm of the p-values of their association with cibersort: B cell naive to WebGestalt.