Basic information
- Full name
- 5'-nucleotidase, cytosolic IA
- Ensembl
- ENSG00000116981.3
- Summary
- Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008]
- Annotation
- Phosphatase
Protein product
- ENST00000235628.1 Primary ENSP00000235628.1 (1 phosphosite)
Phosphosites on the primary protein product
Tumor and normal comparison
Signed p-values | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Data type | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
RNA | -5e-22 | - | -5.4e-29 | - | - | -8.2e-8 | -2.0e-4 | 4.6e-6 | - | -3.6e-9 | - |
protein | -4.1e-7 | - | -2.5e-8 | - | - | -3.2e-5 | - | 0.33 | - | - | - |
mRNA expression at gene level
Protein expression
Phenotype and mutation association
Manhattan plot summarizing associations of phenotypes and mutations across all cohorts and omics data types
Associations of the protein abundance of NT5C1A with phenotypes and mutations
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
HALLMARK_KRAS_SIGNALING_DN | 6.6e-10 | - | 0.59 | - | 2.6e-4 | 2.9e-6 | - | 5.0e-4 | - | - | - | |
xcell: Hematopoietic stem cell | 2.5e-8 | - | 0.039 | - | 6.5e-3 | 5.2e-4 | - | 3.9e-3 | - | - | - | |
HALLMARK_MYOGENESIS | 3.4e-6 | - | 0.039 | - | -0.36 | 5.5e-9 | - | 0.021 | - | - | - | |
xcell: Myeloid dendritic cell | 8.5e-5 | - | 0.059 | - | -0.19 | 1.0e-4 | - | 6.8e-4 | - | - | - | |
HALLMARK_HEME_METABOLISM | 1.8e-4 | - | 0.26 | - | 0.015 | 0.037 | - | 0.062 | - | - | - | |
DISEASE-PSP_Alzheimer's_disease | 6.9e-4 | - | - | - | 6.8e-4 | - | - | - | - | - | - | |
KINASE-PSP_PKACA/PRKACA | 9.8e-4 | - | -0.56 | - | -0.77 | 6.6e-5 | - | 4.8e-4 | - | - | - | |
xcell: stroma score | 1.6e-3 | - | 0.11 | - | -0.53 | 1.7e-4 | - | 0.11 | - | - | - | |
cibersort: Myeloid dendritic cell resting | 2.3e-3 | - | 0.71 | - | -0.78 | 3.9e-3 | - | 1.8e-3 | - | - | - | |
HALLMARK_APICAL_JUNCTION | 3.4e-3 | - | 0.41 | - | -0.05 | 1.6e-6 | - | 0.029 | - | - | - |
Cis-association
Associations between omics data of NT5C1A
Trans-association
Associations of the protein abundance of NT5C1A and the protein abundance of other genes
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
No matching records found |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with to WebGestalt.