TAF12: TATA-box binding protein associated factor 12
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1h3o chain B
1h3o chain D
6mzc chain R
6mzd chain Q
6mzl chain Q
6mzl chain R
6mzm chain R
7edx chain L
7edx chain l
7eg7 chain L
7eg7 chain l
7eg8 chain L
7eg8 chain l
7eg9 chain L
7eg9 chain l
7ega chain L
7ega chain l
7egb chain L
7egb chain l
7egc chain L
7egc chain l
7egd chain L
7egd chain l
7ege chain L
7ege chain l
7egf chain l
7egg chain L
7egi chain L
7egi chain l
7egj chain L
7egj chain l
7ena chain DL
7ena chain Dl
7enc chain DL
7enc chain Dl
7ktr chain G
7kts chain G
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T43 AVVKIPGT PGAGGRL 10 529 48 - 52 35 9 9 18 - 13 5 89 81 61 56 13 4 8 4 20 4 S51 PGAGGRLS PENNQVL 10 1552 122 - 103 79 97 100 99 - 108 62 108 99 110 101 83 19 105 44 95 18 S108 QLARHRKS STLEVKD 3 55 36 - - - - - - - - - 5 5 - - - - - - - 9 S109 LARHRKSS TLEVKDV 4 33 - - - - - - 9 - 5 3 5 4 - - - - 5 2 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T43 AVVKIPGT PGAGGRL 0.026 - 6.9e-6 - - - 8.2e-5 -4.8e-6 - - - S51 PGAGGRLS PENNQVL 9.9e-18 - 2.6e-14 2e-22 - 0.21 3.2e-8 -5.6e-8 -0.16 2.4e-9 0.32 S108 QLARHRKS STLEVKD - - - - - - - - - - - S109 LARHRKSS TLEVKDV - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T43
S51
S108
S109
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T43 S51 S108 S109 protein RNA SCNV methylation CCRCC T43 S51 S108 S109 protein RNA SCNV methylation COAD T43 S51 S108 S109 protein RNA SCNV methylation GBM T43 S51 S108 S109 protein RNA SCNV methylation HNSCC T43 S51 S108 S109 protein RNA SCNV methylation LSCC T43 S51 S108 S109 protein RNA SCNV methylation LUAD T43 S51 S108 S109 protein RNA SCNV methylation OV T43 S51 S108 S109 protein RNA SCNV methylation PDAC T43 S51 S108 S109 protein RNA SCNV methylation UCEC T43 S51 S108 S109 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T43
S51
S108
S109
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T43
S51
S108
S109
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.