cibersort: NK cell activated

LinkedOmicsKB © 2022-2023 Zhang Lab

Basic information

Phenotype
cibersort: NK cell activated
Description
Estimated fraction of activated NK cells in the tumor compared to 21 other immune cells defined by CIBERSORT based on RNA expression data.
Source
https://www.nature.com/articles/nmeth.3337
Method
The R package immunedeconv (V2.0.4) (PMID: 31510660) was used to perform immune cell deconvolution using RNA expression data (TPM). CIBERSORT (PMID: 25822800) was performed in the ‘abs’ mode.
Genes
Gene association

Number of significant genes with P-value ≤ 10-6 for each cohorts are summarized in bar plots. The scatter plot highlights significant associations diven by protein rather than mRNA abundance.

Association of protein abundance of genes

Signed p-values
Gene Meta P BRCA CCRCC COAD GBM HNSCC LSCC LUAD OV PDAC UCEC

* P-values for individual cohorts can be clicked to show the data plots. The rows in the table can be expanded to show results from other omics.

Gene set enrichment analysis

Submit genes and the common logarithm of the p-values of their association with cibersort: NK cell activated to WebGestalt.

Phosphosite association

Number of significant genes with P-value ≤ 10-6 for each cohorts are summarized in the bar plot. The scatter plot highlights significant associations diven by phosphorylation rather than protein abundance.

Signed p-values
Gene Protein Site Meta P BRCA CCRCC COAD GBM HNSCC LSCC LUAD OV PDAC UCEC

* P-values for individual cohorts can be clicked to show the data plots.

Gene set enrichment analysis

Submit phosphorylation sites and the common logarithm of the p-values of their association with cibersort: NK cell activated to WebGestalt.