Protein: ENSP00000222271

COMP:: cartilage oligomeric matrix protein

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S432	FVGDACDSDQDQDGD	1	13	13	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
S459	PNSAQEDSDHDGQGD	1	9	9	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S432	FVGDACDSDQDQDGD	-	-	-	-	-	-	-	-	-	-	-
S459	PNSAQEDSDHDGQGD	-	-	-	-	-	-	-	-	-	-	-

Showing 1 to 2 of 2 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
SBS1 (clock-like)	S432	0.021	0.021	-	-	-	-	-	-	-	-	-
xcell: Common myeloid progenitor	S432	0.053	0.053	-	-	-	-	-	-	-	-	-
KINASE-PSP_Akt1/AKT1	S432	0.074	0.074	-	-	-	-	-	-	-	-	-
cibersort: Myeloid dendritic cell resting	S432	0.098	0.098	-	-	-	-	-	-	-	-	-
cibersort: Eosinophil	S432	0.11	0.11	-	-	-	-	-	-	-	-	-
HALLMARK_GLYCOLYSIS	S432	0.21	0.21	-	-	-	-	-	-	-	-	-
xcell: T cell CD4+ naive	S432	0.24	0.24	-	-	-	-	-	-	-	-	-
HALLMARK_ADIPOGENESIS	S432	0.3	0.3	-	-	-	-	-	-	-	-	-
HALLMARK_BILE_ACID_METABOLISM	S432	0.33	0.33	-	-	-	-	-	-	-	-	-
KINASE-PSP_CK2A1/CSNK2A1	S432	0.33	0.33	-	-	-	-	-	-	-	-	-

Showing 1 to 10 of 516 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
ACP5	S432	-0.022	-0.022	-	-	-	-	-	-	-	-	-
PTPN2	S432	-0.036	-0.036	-	-	-	-	-	-	-	-	-
MTMR14	S432	-0.043	-0.043	-	-	-	-	-	-	-	-	-
PTPRA	S432	-0.064	-0.064	-	-	-	-	-	-	-	-	-
INPPL1	S432	-0.097	-0.097	-	-	-	-	-	-	-	-	-
CTDSPL2	S432	-0.15	-0.15	-	-	-	-	-	-	-	-	-
FIG4	S432	-0.15	-0.15	-	-	-	-	-	-	-	-	-
PLPP3	S432	-0.16	-0.16	-	-	-	-	-	-	-	-	-
FBP2	S432	-0.17	-0.17	-	-	-	-	-	-	-	-	-
PTPN6	S432	-0.18	-0.18	-	-	-	-	-	-	-	-	-

Showing 1 to 10 of 480 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000222271Gene: COMP

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000222271
Gene: COMP